ID A0A087RG21_APTFO Unreviewed; 71 AA.
AC A0A087RG21;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Mediator of RNA polymerase II transcription subunit 9 {ECO:0000256|ARBA:ARBA00020636, ECO:0000256|RuleBase:RU364145};
DE AltName: Full=Mediator complex subunit 9 {ECO:0000256|ARBA:ARBA00031260, ECO:0000256|RuleBase:RU364145};
GN Name=MED9 {ECO:0000256|RuleBase:RU364145};
GN ORFNames=AS27_12300 {ECO:0000313|EMBL:KFM12425.1};
OS Aptenodytes forsteri (Emperor penguin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC Aptenodytes.
OX NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM12425.1, ECO:0000313|Proteomes:UP000053286};
RN [1] {ECO:0000313|EMBL:KFM12425.1, ECO:0000313|Proteomes:UP000053286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM12425.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the Mediator complex, a coactivator involved in
CC the regulated transcription of nearly all RNA polymerase II-dependent
CC genes. Mediator functions as a bridge to convey information from gene-
CC specific regulatory proteins to the basal RNA polymerase II
CC transcription machinery. Mediator is recruited to promoters by direct
CC interactions with regulatory proteins and serves as a scaffold for the
CC assembly of a functional preinitiation complex with RNA polymerase II
CC and the general transcription factors. {ECO:0000256|ARBA:ARBA00025687,
CC ECO:0000256|RuleBase:RU364145}.
CC -!- SUBUNIT: Component of the Mediator complex.
CC {ECO:0000256|RuleBase:RU364145}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU364145}.
CC -!- SIMILARITY: Belongs to the Mediator complex subunit 9 family.
CC {ECO:0000256|ARBA:ARBA00008089, ECO:0000256|RuleBase:RU364145}.
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DR EMBL; KL226347; KFM12425.1; -; Genomic_DNA.
DR RefSeq; XP_009284721.1; XM_009286446.1.
DR RefSeq; XP_009284722.1; XM_009286447.1.
DR RefSeq; XP_009284723.1; XM_009286448.2.
DR AlphaFoldDB; A0A087RG21; -.
DR STRING; 9233.A0A087RG21; -.
DR GeneID; 103904905; -.
DR KEGG; afor:103904905; -.
DR CTD; 55090; -.
DR OrthoDB; 4616030at2759; -.
DR Proteomes; UP000053286; Unassembled WGS sequence.
DR GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 6.10.280.10; Mediator complex, subunit Med21; 1.
DR InterPro; IPR037212; Med7/Med21-like.
DR InterPro; IPR011425; Med9.
DR InterPro; IPR039242; MED9_metazoa.
DR PANTHER; PTHR20844:SF0; MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 9; 1.
DR PANTHER; PTHR20844; MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 9; 1.
DR Pfam; PF07544; Med9; 1.
DR SUPFAM; SSF140718; Mediator hinge subcomplex-like; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|RuleBase:RU364145};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364145};
KW Reference proteome {ECO:0000313|Proteomes:UP000053286};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU364145};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU364145}.
SQ SEQUENCE 71 AA; 8403 MW; E142A1D2BB469BA9 CRC64;
MDKDSQDVHQ VLNELKNKFQ ETRKLISSMP GIGVSPEQQQ QQLQNLREQV RTKNELLQKY
KSLCMFEIPK E
//
