ID A0A087RGW6_APTFO Unreviewed; 386 AA.
AC A0A087RGW6;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Endophilin-B1 {ECO:0000256|ARBA:ARBA00018361};
DE AltName: Full=Endophilin-B2 {ECO:0000256|ARBA:ARBA00040331};
DE AltName: Full=SH3 domain-containing GRB2-like protein B1 {ECO:0000256|ARBA:ARBA00033266};
DE AltName: Full=SH3 domain-containing GRB2-like protein B2 {ECO:0000256|ARBA:ARBA00042180};
DE Flags: Fragment;
GN ORFNames=AS27_01582 {ECO:0000313|EMBL:KFM12720.1};
OS Aptenodytes forsteri (Emperor penguin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC Aptenodytes.
OX NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM12720.1, ECO:0000313|Proteomes:UP000053286};
RN [1] {ECO:0000313|EMBL:KFM12720.1, ECO:0000313|Proteomes:UP000053286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM12720.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homodimer, and heterodimer with SH3GLB1.
CC {ECO:0000256|ARBA:ARBA00038771}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Golgi
CC apparatus membrane {ECO:0000256|ARBA:ARBA00004395}; Peripheral membrane
CC protein {ECO:0000256|ARBA:ARBA00004395}. Mitochondrion outer membrane
CC {ECO:0000256|ARBA:ARBA00004450}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004450}.
CC -!- SIMILARITY: Belongs to the endophilin family.
CC {ECO:0000256|ARBA:ARBA00006697}.
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DR EMBL; KL226358; KFM12720.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087RGW6; -.
DR STRING; 9233.A0A087RGW6; -.
DR Proteomes; UP000053286; Unassembled WGS sequence.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR CDD; cd07617; BAR_Endophilin_B2; 1.
DR CDD; cd11945; SH3_Endophilin_B1; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR028503; SH3GLB_SH3.
DR PANTHER; PTHR14167:SF68; ENDOPHILIN-B2; 1.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR Pfam; PF03114; BAR; 1.
DR Pfam; PF14604; SH3_9; 1.
DR SMART; SM00721; BAR; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51021; BAR; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00022787};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00022787};
KW Reference proteome {ECO:0000313|Proteomes:UP000053286};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 5..270
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT DOMAIN 326..386
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFM12720.1"
FT NON_TER 386
FT /evidence="ECO:0000313|EMBL:KFM12720.1"
SQ SEQUENCE 386 AA; 43163 MW; ADA8061DE4831AB4 CRC64;
LQFTEEKLGQ AEKTELDAHF ENLLARADFT KNWTEKILRQ TEVLLQPNPS ARVEEFLYEK
LDRKVPSRVT NGELLAQYMT EAANDFGPGT PYGKTLIKVG ETQRRLRLGA AERDFIHSAS
INFLTPLRNF LEGDWRTISK ERRILQNRRL DLDACKARLK KAKAAEAKAA AVPDFQETRP
RNYVLSASAS ALWSDEVEKA EHELRLTQTE FDRQAEVTRL LLEGISSTHV NHLRCLHEFV
ESQTNYYAQC YQYMLDLQKQ LGRFSGTFVG NAESTSPPPA ATSLPAVAAA TLPAVPTIPV
VPTIVGVPNT MAESVLNPNE VKPPASGTRK ARVLYDYEAA DSTELALLAD EMITVYSLPG
MDPDWLIGER GNQKGKVPVT YLELLS
//
