ID A0A087RHX7_APTFO Unreviewed; 2117 AA.
AC A0A087RHX7;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Dedicator of cytokinesis protein 7 {ECO:0000313|EMBL:KFM13081.1};
DE Flags: Fragment;
GN ORFNames=AS27_01071 {ECO:0000313|EMBL:KFM13081.1};
OS Aptenodytes forsteri (Emperor penguin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC Aptenodytes.
OX NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM13081.1, ECO:0000313|Proteomes:UP000053286};
RN [1] {ECO:0000313|EMBL:KFM13081.1, ECO:0000313|Proteomes:UP000053286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM13081.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DOCK family. {ECO:0000256|PROSITE-
CC ProRule:PRU00983}.
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DR EMBL; KL226373; KFM13081.1; -; Genomic_DNA.
DR STRING; 9233.A0A087RHX7; -.
DR Proteomes; UP000053286; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd08696; C2_Dock-C; 1.
DR CDD; cd11703; DHR2_DOCK7; 1.
DR Gene3D; 1.20.58.740; -; 1.
DR Gene3D; 1.25.40.410; -; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR InterPro; IPR037808; C2_Dock-C.
DR InterPro; IPR027007; C2_DOCK-type_domain.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR026791; DOCK.
DR InterPro; IPR021816; DOCK_C/D_N.
DR InterPro; IPR043161; DOCK_C_lobe_A.
DR InterPro; IPR043162; DOCK_C_lobe_C.
DR InterPro; IPR027357; DOCKER_dom.
DR InterPro; IPR046769; DOCKER_Lobe_A.
DR InterPro; IPR046770; DOCKER_Lobe_B.
DR InterPro; IPR046773; DOCKER_Lobe_C.
DR PANTHER; PTHR23317; DEDICATOR OF CYTOKINESIS DOCK; 1.
DR PANTHER; PTHR23317:SF78; DEDICATOR OF CYTOKINESIS PROTEIN 7; 1.
DR Pfam; PF06920; DHR-2_Lobe_A; 1.
DR Pfam; PF20422; DHR-2_Lobe_B; 1.
DR Pfam; PF20421; DHR-2_Lobe_C; 1.
DR Pfam; PF14429; DOCK-C2; 1.
DR Pfam; PF11878; DOCK_C-D_N; 1.
DR PROSITE; PS51650; C2_DOCK; 1.
DR PROSITE; PS51651; DOCKER; 1.
PE 3: Inferred from homology;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000053286}.
FT DOMAIN 549..715
FT /note="C2 DOCK-type"
FT /evidence="ECO:0000259|PROSITE:PS51650"
FT DOMAIN 1657..2091
FT /note="DOCKER"
FT /evidence="ECO:0000259|PROSITE:PS51651"
FT REGION 125..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 876..955
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 132..146
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 876..902
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 932..955
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFM13081.1"
FT NON_TER 2117
FT /evidence="ECO:0000313|EMBL:KFM13081.1"
SQ SEQUENCE 2117 AA; 239873 MW; FD7D9B232624E699 CRC64;
RTVAAEVRKQ ISGQYGGSPQ LLKNLNIGGS VSHHTTVPLT EAVDPVELED YLITHPIAVE
SGPLRDLLEF PPDDIEVVYT PRECRTLVSA VPEESEMDPH VRDCVRSYTE DWAIVNRKYH
KLGTGFNPNT LDKQKERQKG LPKQIFESDE APDGNSYQDE QDDLKRRSMS IDDTPRGSWA
CSIFDLKNSL PDALLPNLLD RTPNEEIDHH NEDQRKSSRH KELFALHPAP DEEEPIERLS
VPEVPKEHFG QRLLVKCLSL KFEIEIEPIF ASLALYDVKE KKKISENFYF DLNSEQMKGM
LRPHVPPAAI STLARSAIFS ITYPSQDVFL VIKLEKVLQQ GDIGECAEPY MIFKESDAAK
NKEKLEKLKC QAEQFCQRLG KYRMPFAWTA IHLMNIVSSA GSLERDSTEV EVGTGERKGS
WSERRNSSIV GRRSLERTTS GDEACNLTSF RPATLTVTNF FKQEGDRLSD EDLYKFLADM
RRPSSVLRRL RPITAQLKID ISPAPENPHY CLTPELLQVK LYPDSRVRPT REILEFPARD
VYVPNTTYRN LLYVYPQSLN FANRQGSARN ITVKVQFMYG EDPSNAMPVI FGKSSCPEFS
KEAYTAVVYH NRSPDFHEEI KIKLPATLTD HHHLLFTFYH VSCQQKQNTP LETPVGYTWI
PMLQNGRLKT GQFCLPVSLE KPPQAYSVLS PEVPLPGMKW VDNHKGVFNV EVVAVSSLHT
QDPYLDKFFA LVHALDEHMF PVRIGDMRII ENNLENELKS SISALNSSQL EPVVRFLHLL
LDKLILLVVR PPVIAGQIVN LGQASFEAMA SIINRLHKNL DGNQDQHGRN SLLASYIYYV
FRLPNTYPNS PSPGPGGLGG SVHYATMARS AVRPASLNLN RSRSLSNSNP DISGTPTSPD
DEVRSIIGSK GLDRSNSWVN TGGPKAAPWG SNPSPSAEST QATDRSCNRM SSHTETSSFL
QTLTGRLPTK KLFHEELALQ WVVCSGSVRE AALQQAWFFF ELMVKSMVHH LYFADKLDAP
RKNRFPERFM DDVTALVSTI AGDIVSRFQK DTEMVERLNT SLAFFLNDLL SIMDRGFVFA
LIKTCYKQVS SKLYSLTNPS NLASLRLDFL RIICSHEHYV TLNLPCSLLT PPASPSPSVS
SATSQSSGFS TNVQDQKIAN MFELSVPFRQ QHYLAGLVLT ELAVILDPDA EGLFGLHKKV
INMVHNLLSS HDSDPRYADP QVKARVAMLY LPLIGVIMET VPQLYDFTES HNQRGRPSCI
AVDDYESEGG SMISQTVAMA IAGTSVPQLT RPSSFLLASS SGRQHSTFST ESSRSLLICL
LWVLKNADES VLQKWFTDLS VLQLNRLLDL LYLCVSCFEY KGKKVFERMN SLTFKKSKDM
RAKLEEAILG SIGARQEMVR RSRGQLERSP SGSAFGSQEN LRWRKDMTHW RQNTEKLDKS
RAEIEHEALI DGNLATEANL IILDTLEIVV QTVSVTESKE SILGGVLKVL LHSMACNQSA
LYLQHCFATQ RALVSKFPEL LFEEETEQCA DLCLRLLRHC SSSISTIRSH ASASLYLLMR
QNFEIGNNFA RVKMQVTMSL SSLVGTSQNF NEEFLRRSLK TILTYAEEDL ELRETTFPDQ
VQDLVFNLHM ILSDTVKMKE HQEDPEMLID LMYRIAKGYQ NSPDLRLTWL QNMAGKHSER
SNHAESAQCL VHSAALVAEY LSMLEDRKYL PVGCVTFQNI SSNVLEESAV SDDVVSPDEE
GICSGKYFTE AGLVGLLEQA AASFSMAGMY EAVNEVYKVL IPIHEANRDA KKLSTIHGKL
QEAFSKIVHQ DGKRMFGTYF RVGFYGTKFG DLDEQEFVYK EPAITKLAEI SHRLEGFYGE
RFGEDVLEVI KDSNPVDKCK LDPNKAYIQI TYVEPYFDTY EMKDRITYFD KNYNLRRFMY
CTPFTLDGRA HGELHEQFKR KTILTTSHAF PYIKTRINVI HKEEIILTPI EVAIEDMQKK
TQELAFATHQ DPADPKMLQM VLQGSVGTTV NQGPLEVAQV FLSEIPNDPK LFRHHNKLRL
CFKDFTKRCE DALRKNKSLI GPDQKEYQRE LERNYHRLKE ALQPLINRKI PQLYKAVLPV
TCHRDSFSRM SLRKMDI
//
