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Database: UniProt
Entry: A0A087RIB7_APTFO
LinkDB: A0A087RIB7_APTFO
Original site: A0A087RIB7_APTFO 
ID   A0A087RIB7_APTFO        Unreviewed;       233 AA.
AC   A0A087RIB7;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   RecName: Full=Voltage-dependent calcium channel gamma-1 subunit {ECO:0000256|ARBA:ARBA00019950, ECO:0000256|RuleBase:RU363085};
DE   AltName: Full=Dihydropyridine-sensitive L-type, skeletal muscle calcium channel subunit gamma {ECO:0000256|ARBA:ARBA00029680, ECO:0000256|RuleBase:RU363085};
DE   Flags: Fragment;
GN   ORFNames=AS27_03013 {ECO:0000313|EMBL:KFM13221.1};
OS   Aptenodytes forsteri (Emperor penguin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC   Aptenodytes.
OX   NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM13221.1, ECO:0000313|Proteomes:UP000053286};
RN   [1] {ECO:0000313|EMBL:KFM13221.1, ECO:0000313|Proteomes:UP000053286}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM13221.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Regulatory subunit of the voltage-gated calcium channel that
CC       gives rise to L-type calcium currents in skeletal muscle. Regulates
CC       channel inactivation kinetics. {ECO:0000256|ARBA:ARBA00003367,
CC       ECO:0000256|RuleBase:RU363085}.
CC   -!- SUBUNIT: Component of a calcium channel complex consisting of a pore-
CC       forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or
CC       CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta,
CC       gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either
CC       CACNB1 or CACNB2. {ECO:0000256|RuleBase:RU363085}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane, sarcolemma
CC       {ECO:0000256|ARBA:ARBA00004415}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004415}. Membrane
CC       {ECO:0000256|RuleBase:RU363085}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU363085}.
CC   -!- SIMILARITY: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
CC       {ECO:0000256|ARBA:ARBA00007111, ECO:0000256|RuleBase:RU363085}.
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DR   EMBL; KL226380; KFM13221.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A087RIB7; -.
DR   STRING; 9233.A0A087RIB7; -.
DR   Proteomes; UP000053286; Unassembled WGS sequence.
DR   GO; GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.
DR   GO; GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
DR   Gene3D; 1.20.140.150; -; 1.
DR   InterPro; IPR004031; PMP22/EMP/MP20/Claudin.
DR   InterPro; IPR005421; VDCC_g1su.
DR   InterPro; IPR008368; VDCC_gsu.
DR   PANTHER; PTHR15025:SF1; VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-1 SUBUNIT; 1.
DR   PANTHER; PTHR15025; VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-1 SUBUNIT-RELATED; 1.
DR   Pfam; PF13903; Claudin_2; 1.
DR   PRINTS; PR01792; VDCCGAMMA.
DR   PRINTS; PR01601; VDCCGAMMA1.
PE   3: Inferred from homology;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|RuleBase:RU363085};
KW   Calcium channel {ECO:0000256|ARBA:ARBA00022673,
KW   ECO:0000256|RuleBase:RU363085};
KW   Calcium transport {ECO:0000256|ARBA:ARBA00022568,
KW   ECO:0000256|RuleBase:RU363085};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000256|RuleBase:RU363085};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW   ECO:0000256|RuleBase:RU363085};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363085};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053286};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363085};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363085};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363085};
KW   Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882,
KW   ECO:0000256|RuleBase:RU363085}.
FT   TRANSMEM        16..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363085"
FT   TRANSMEM        116..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363085"
FT   TRANSMEM        152..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363085"
FT   TRANSMEM        189..215
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363085"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFM13221.1"
FT   NON_TER         233
FT                   /evidence="ECO:0000313|EMBL:KFM13221.1"
SQ   SEQUENCE   233 AA;  26101 MW;  D4051841F32168EA CRC64;
     GTPVQSRMDQ SKPLKVRLTF SVILVGVSLL FTAVVTDHWA VLSPRVEEYN ATCEAAHFGL
     WRLCIKRIFM QEQGPKVKGC GPISLPGEHN CSYFKHFTPG QSSEIFEVTT QKEYSISAAA
     IAIFSIGFAI IGTICVLLSF SKKRDYLLKP ASMFYTFAGL CIIISVEVMR QSVKRMIDSE
     ETVWIEYTYS WSFACACASF VLLFICGITL LLIALPPFPQ NPWETCMDAE PEH
//
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