ID A0A087SAM9_AUXPR Unreviewed; 1068 AA.
AC A0A087SAM9;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Clathrin heavy chain 1 {ECO:0000313|EMBL:KFM22783.1};
GN ORFNames=F751_2974 {ECO:0000313|EMBL:KFM22783.1};
OS Auxenochlorella protothecoides (Green microalga) (Chlorella
OS protothecoides).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Chlorellales; Chlorellaceae; Auxenochlorella.
OX NCBI_TaxID=3075 {ECO:0000313|EMBL:KFM22783.1, ECO:0000313|Proteomes:UP000028924};
RN [1] {ECO:0000313|EMBL:KFM22783.1, ECO:0000313|Proteomes:UP000028924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0710 {ECO:0000313|EMBL:KFM22783.1,
RC ECO:0000313|Proteomes:UP000028924};
RX PubMed=25012212; DOI=10.1186/1471-2164-15-582;
RA Gao C., Wang Y., Shen Y., Yan D., He X., Dai J., Wu Q.;
RT "Oil accumulation mechanisms of the oleaginous microalga Chlorella
RT protothecoides revealed through its genome, transcriptomes, and
RT proteomes.";
RL BMC Genomics 15:582-582(2014).
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane
CC {ECO:0000256|ARBA:ARBA00004180}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004180}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004180}. Membrane, coated pit
CC {ECO:0000256|ARBA:ARBA00004277}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004277}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004277}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- SIMILARITY: Belongs to the clathrin heavy chain family.
CC {ECO:0000256|ARBA:ARBA00009535}.
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DR EMBL; KL662081; KFM22783.1; -; Genomic_DNA.
DR RefSeq; XP_011395648.1; XM_011397346.1.
DR AlphaFoldDB; A0A087SAM9; -.
DR STRING; 3075.A0A087SAM9; -.
DR GeneID; 23614365; -.
DR KEGG; apro:F751_2974; -.
DR eggNOG; KOG0985; Eukaryota.
DR OrthoDB; 5474327at2759; -.
DR Proteomes; UP000028924; Unassembled WGS sequence.
DR GO; GO:0030132; C:clathrin coat of coated pit; IEA:InterPro.
DR GO; GO:0030130; C:clathrin coat of trans-Golgi network vesicle; IEA:InterPro.
DR GO; GO:0071439; C:clathrin complex; IEA:InterPro.
DR GO; GO:0032051; F:clathrin light chain binding; IEA:InterPro.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR Gene3D; 2.130.10.110; Clathrin heavy-chain terminal domain; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000547; Clathrin_H-chain/VPS_repeat.
DR InterPro; IPR015348; Clathrin_H-chain_linker_core.
DR InterPro; IPR016025; Clathrin_H-chain_N.
DR InterPro; IPR022365; Clathrin_H-chain_propeller_rpt.
DR InterPro; IPR016341; Clathrin_heavy_chain.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR10292:SF1; CLATHRIN HEAVY CHAIN; 1.
DR PANTHER; PTHR10292; CLATHRIN HEAVY CHAIN RELATED; 1.
DR Pfam; PF00637; Clathrin; 4.
DR Pfam; PF09268; Clathrin-link; 1.
DR Pfam; PF13838; Clathrin_H_link; 1.
DR Pfam; PF01394; Clathrin_propel; 1.
DR PIRSF; PIRSF002290; Clathrin_H_chain; 1.
DR SMART; SM00299; CLH; 3.
DR SUPFAM; SSF48371; ARM repeat; 3.
DR SUPFAM; SSF50989; Clathrin heavy-chain terminal domain; 1.
DR PROSITE; PS50236; CHCR; 4.
PE 3: Inferred from homology;
KW Coated pit {ECO:0000256|ARBA:ARBA00023176};
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000028924};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 338..360
FT /note="Clathrin heavy chain linker core motif"
FT /evidence="ECO:0000259|Pfam:PF09268"
SQ SEQUENCE 1068 AA; 115063 MW; B3E746801434B393 CRC64;
MATGAAPINL QNLGIQNANI TFTNVTLESE KYICVRETSP TNQLVIIDLS NPSSPQRRPI
TADSALMNPG SQIIALKAAV PGVTGDNLQI FDLAAKAKLK SVQFPQSVVF WKWVSPGRLG
LVTATSVYHW DLEGDAPPAK VFDRAANLEG TQIITYRVDA AGRWCVLVGI APGAPDRPAL
VKGFMQLYSV DQARSQALEA HAAAFASLAL PGRADPVPVI AFAQKTAAAG GAVTSKLHVI
ELGLPGKTSL KRSAELFFPP EFADDFPVSM QIGDKYGLVY VVTKLGLLFV YDLETATAIF
RTRISADPFF IAAPAPSTGG FVAINRRGQV LAGGPAPDAI IPFIAGQLQN VELALALAQR
GNLPGAEGLV VQSFQRQYAA GQYREAAETA ARSPQGSLRT RETVEAFKRV PAVPGQTSPL
LVYFGTVLAR EALNAYESVE LGRLVLAQGK KPLLDGWWRD GKLSASEELG DLFRGAGDWD
AALAVYRAAG AQGKVVEALA AKGDFEELGR YAATTGSQPD YLFLLQSLLR DSPEAAVGLA
KAVARQPGPP LDLNTMADLF LQRNAVKEAT AFLLDALADD APAHAALQTK LLEINLVTAP
AVADAILGAG GLTRYDRPRV AQLCEKAGLY ARALAHYTDL ADIKRVLGNA RAIDPAALVE
YFGTLSAEWA LDCLRVLLEA DPAANLELVV RVAREYSEQL TVARIVALFE AAGSWDGLYF
FLGGVLAGSE DPEVHYKYIE AAARTGQVKE VERVTRESSC YPPDRVKTFL MEANLPDARP
LINVCDRHGF VPDLTLYLYK KSMLRYIEGY VQKVSPAKTP AVVGALLDAE ADEAFITNLV
LSVRSLVPVA ELVEAVESRN RLKMLNPLLE QLVSEGSRDP GVHDALGKII VDANTNPEHF
LTTNPYYDSL VVGRFAERRD PGLACVAYKR GQCDEALVAC TNKHAMFKLQ ARYVVERADA
GLWESVLGPE NASRRQLIDQ VVSTALPECK NPEQVSVAVK AFMGADLQAP LIELLEKIVL
NNSSFSNNHN LQNLLIITAI KADKARVKDY IHRLDNFDGP AVGEIAVG
//
