ID A0A087SHN1_AUXPR Unreviewed; 641 AA.
AC A0A087SHN1;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Translation initiation factor IF-2 {ECO:0000313|EMBL:KFM25235.1};
GN ORFNames=F751_3915 {ECO:0000313|EMBL:KFM25235.1};
OS Auxenochlorella protothecoides (Green microalga) (Chlorella
OS protothecoides).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Chlorellales; Chlorellaceae; Auxenochlorella.
OX NCBI_TaxID=3075 {ECO:0000313|EMBL:KFM25235.1, ECO:0000313|Proteomes:UP000028924};
RN [1] {ECO:0000313|EMBL:KFM25235.1, ECO:0000313|Proteomes:UP000028924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0710 {ECO:0000313|EMBL:KFM25235.1,
RC ECO:0000313|Proteomes:UP000028924};
RX PubMed=25012212; DOI=10.1186/1471-2164-15-582;
RA Gao C., Wang Y., Shen Y., Yan D., He X., Dai J., Wu Q.;
RT "Oil accumulation mechanisms of the oleaginous microalga Chlorella
RT protothecoides revealed through its genome, transcriptomes, and
RT proteomes.";
RL BMC Genomics 15:582-582(2014).
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. IF-2 subfamily.
CC {ECO:0000256|ARBA:ARBA00007733}.
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DR EMBL; KL662114; KFM25235.1; -; Genomic_DNA.
DR RefSeq; XP_011398127.1; XM_011399825.1.
DR AlphaFoldDB; A0A087SHN1; -.
DR STRING; 3075.A0A087SHN1; -.
DR GeneID; 23615306; -.
DR KEGG; apro:F751_3915; -.
DR eggNOG; KOG1145; Eukaryota.
DR OrthoDB; 169393at2759; -.
DR Proteomes; UP000028924; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd01887; IF2_eIF5B; 1.
DR CDD; cd03692; mtIF2_IVc; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 3.40.50.10050; Translation initiation factor IF- 2, domain 3; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR015760; TIF_IF2.
DR InterPro; IPR023115; TIF_IF2_dom3.
DR InterPro; IPR036925; TIF_IF2_dom3_sf.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43381:SF20; TRANSLATION INITIATION FACTOR IF-2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43381; TRANSLATION INITIATION FACTOR IF-2-RELATED; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF11987; IF-2; 1.
DR SUPFAM; SSF52156; Initiation factor IF2/eIF5b, domain 3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 2.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540,
KW ECO:0000313|EMBL:KFM25235.1};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000028924}.
FT DOMAIN 198..373
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 34..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..64
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 641 AA; 67473 MW; 5C21BBA0E4FA6438 CRC64;
MGTRVAIRFA WPSGLVRLPS GWSIHQAHPW DLHRSRTASP GKATPGGAAR REARHPRTPE
QQREWLKATG KWIDRSAPGA TWKHPRTPEE QREWLRANGM LWEAGAQPRR HPRTPEEQRE
WLRAQGKLGP DQAPRPKPVR AAPAVQPPVV IPADVTVLRL ASLFGCPLSR LEGILASLGS
PPGSEQELVS PEDAELAAME LGVAAVLDPE AAATTLLDAL RRTALAAREA GGITQHIGAF
SFPLPASGTA LTFLDTPGHA AFCAMRARGA AVTDIVVLVV AADDGVMPQT REALAHARAA
GCPVVVALTK CDVPGAAPAR VRAALLSLGL ELEEAGGTVQ VVEVAAPRGT GLDALEEALL
LQAEMMDLRA SPSARAAGVV VEARLDRGRG PVATVVVRQG TLRAGDVVVA GAEWGRVRAV
RGPARARADV AGSVEAVCDA LAALSCRELE LRVVHAGVGP VSASDVQLAV PLRARVVAFG
VRTAGAAVDA ELRRHGLTLH RHDVIYKLLE ELGEVMLGEA PRVEREVVAG EAAVLQVFDV
KATRGREAAV VAGCRVQEGS LRASHTFRVL RAGELVHEGP CASLRRVKLG VEAVGKGGEC
GVALTGFSHF RPGDVLRCIS VEMVRPEALT ASAPEGAAQA P
//
