ID A0A087SNX8_AUXPR Unreviewed; 912 AA.
AC A0A087SNX8;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 2 {ECO:0000313|EMBL:KFM27432.1};
GN ORFNames=F751_1209 {ECO:0000313|EMBL:KFM27432.1};
OS Auxenochlorella protothecoides (Green microalga) (Chlorella
OS protothecoides).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Chlorellales; Chlorellaceae; Auxenochlorella.
OX NCBI_TaxID=3075 {ECO:0000313|EMBL:KFM27432.1, ECO:0000313|Proteomes:UP000028924};
RN [1] {ECO:0000313|EMBL:KFM27432.1, ECO:0000313|Proteomes:UP000028924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0710 {ECO:0000313|EMBL:KFM27432.1,
RC ECO:0000313|Proteomes:UP000028924};
RX PubMed=25012212; DOI=10.1186/1471-2164-15-582;
RA Gao C., Wang Y., Shen Y., Yan D., He X., Dai J., Wu Q.;
RT "Oil accumulation mechanisms of the oleaginous microalga Chlorella
RT protothecoides revealed through its genome, transcriptomes, and
RT proteomes.";
RL BMC Genomics 15:582-582(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004287};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004287};
CC Cytoplasmic side {ECO:0000256|ARBA:ARBA00004287}.
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DR EMBL; KL662146; KFM27432.1; -; Genomic_DNA.
DR RefSeq; XP_011400399.1; XM_011402097.1.
DR AlphaFoldDB; A0A087SNX8; -.
DR STRING; 3075.A0A087SNX8; -.
DR GeneID; 23612600; -.
DR KEGG; apro:F751_1209; -.
DR eggNOG; KOG0929; Eukaryota.
DR OrthoDB; 325165at2759; -.
DR Proteomes; UP000028924; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR InterPro; IPR032629; DCB_dom.
DR InterPro; IPR032691; Mon2/Sec7/BIG1-like_HUS.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR10663:SF375; LD29171P; 1.
DR Pfam; PF16213; DCB; 1.
DR Pfam; PF01369; Sec7; 1.
DR Pfam; PF12783; Sec7-like_HUS; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000028924};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 544..713
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT REGION 131..241
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 254..283
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 335..357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 226..241
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 912 AA; 95600 MW; E464BD66308FC8AC CRC64;
MLQAACSSGA PSIMDPALGT LHKLVAHAFL QGESSSSGRG DDGTIVTQVV TMVARTGVST
TPAVQLGMVR ALLTAVTAEH FVPHGDCLMQ AVRAVFNLAI GSSDPGIQAT AKSALLQMLN
TVLKRVDHQV MTPMGVSPGG PTPTLHRRMS TPTSQASLPT PYPYPPALES VDEEGASAPQ
SGADFVPPRA DGEGAGPRSG DESTKPGEQQ RVPGSEVSPA SGRPSPDRAD HAEDEAEWRD
DPATLEAAAL AWGERVASAS ESREAAAPGA PAPSPPGSPS AADLRQSELA PIATPTAAIE
LHSRSMARED IRTAQMATMA EQADLRGLER ALEELPASGP RPGDEGRSKA ETPPDPRRAL
MHSRRASAWR LLTTIERDAI TVLGAMCKLG ARETSWGAVE TVLHEGKLLA LELLTRVLCD
PLHDWLGVRP EFAGELRAPL CLVLLRNCMP ESVFQAEAAL EGLLPICSSP QILVDVFVNY
DCSLQASNLY ERSIKALGRM ASLTGSEGFG PPAATKRLKE AALKALLAVV SSLDTWAGPI
KSRMRRLVES GLVGPSALEV AAFLREHGPR LKKEALGEYF GHHEEFEMTV MHEFIAAQAF
TETTLDAALR QLLVDFRLPG EAQKIDRIME AFAARYCACN PNAFPTTDGA YLLSFAIIML
NTDAHNPMAD RRISEDDFLV APLWPGAAAW DKAHGVDVER RRLASLTREV VAAGGTAGNL
WHSATHAEHA RPMLQAGAAP LAAGLAAALA DAASPPEVAR ALAGLERAAA LAALLSVPEL
LEELCAVLAR GAGLEGGAED GASRVAGASL PPPGSPAEAK QVACLACLLK VATCPEATYF
GAVWIVLLRA LSALDALLAR LAPPAGDAAA AAAAELSWLT AVFSRRACQS SSPLTCMAPS
APLRQATPGP AR
//
