ID A0A087SQC2_AUXPR Unreviewed; 511 AA.
AC A0A087SQC2;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=glycerol kinase {ECO:0000256|ARBA:ARBA00012099};
DE EC=2.7.1.30 {ECO:0000256|ARBA:ARBA00012099};
DE AltName: Full=ATP:glycerol 3-phosphotransferase {ECO:0000256|ARBA:ARBA00043149};
GN ORFNames=F751_5262 {ECO:0000313|EMBL:KFM27926.1};
OS Auxenochlorella protothecoides (Green microalga) (Chlorella
OS protothecoides).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Chlorellales; Chlorellaceae; Auxenochlorella.
OX NCBI_TaxID=3075 {ECO:0000313|EMBL:KFM27926.1, ECO:0000313|Proteomes:UP000028924};
RN [1] {ECO:0000313|EMBL:KFM27926.1, ECO:0000313|Proteomes:UP000028924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0710 {ECO:0000313|EMBL:KFM27926.1,
RC ECO:0000313|Proteomes:UP000028924};
RX PubMed=25012212; DOI=10.1186/1471-2164-15-582;
RA Gao C., Wang Y., Shen Y., Yan D., He X., Dai J., Wu Q.;
RT "Oil accumulation mechanisms of the oleaginous microalga Chlorella
RT protothecoides revealed through its genome, transcriptomes, and
RT proteomes.";
RL BMC Genomics 15:582-582(2014).
CC -!- PATHWAY: Polyol metabolism; glycerol degradation via glycerol kinase
CC pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
CC {ECO:0000256|ARBA:ARBA00005190}.
CC -!- SIMILARITY: Belongs to the FGGY kinase family.
CC {ECO:0000256|ARBA:ARBA00009156, ECO:0000256|RuleBase:RU003733}.
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DR EMBL; KL662159; KFM27926.1; -; Genomic_DNA.
DR RefSeq; XP_011400933.1; XM_011402631.1.
DR AlphaFoldDB; A0A087SQC2; -.
DR STRING; 3075.A0A087SQC2; -.
DR GeneID; 23616653; -.
DR KEGG; apro:F751_5262; -.
DR eggNOG; KOG2517; Eukaryota.
DR OrthoDB; 2734344at2759; -.
DR UniPathway; UPA00618; UER00672.
DR Proteomes; UP000028924; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004370; F:glycerol kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd07769; FGGY_GK; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000577; Carb_kinase_FGGY.
DR InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR InterPro; IPR018485; FGGY_C.
DR InterPro; IPR018484; FGGY_N.
DR InterPro; IPR005999; Glycerol_kin.
DR NCBIfam; TIGR01311; glycerol_kin; 1.
DR PANTHER; PTHR10196:SF69; GLYCEROL KINASE; 1.
DR PANTHER; PTHR10196; SUGAR KINASE; 1.
DR Pfam; PF02782; FGGY_C; 1.
DR Pfam; PF00370; FGGY_N; 1.
DR PIRSF; PIRSF000538; GlpK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS00933; FGGY_KINASES_1; 1.
DR PROSITE; PS00445; FGGY_KINASES_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Glycerol metabolism {ECO:0000256|ARBA:ARBA00022798};
KW Kinase {ECO:0000256|RuleBase:RU003733, ECO:0000313|EMBL:KFM27926.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000028924};
KW Transferase {ECO:0000256|RuleBase:RU003733}.
FT DOMAIN 6..253
FT /note="Carbohydrate kinase FGGY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00370"
FT DOMAIN 262..452
FT /note="Carbohydrate kinase FGGY C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02782"
SQ SEQUENCE 511 AA; 53875 MW; 545E39E616D5D094 CRC64;
MVQDVIGSID QGTQSTRFFL YDKDLNIVAK SQVPLAAATP HAGWVEQDAE AIIASVSEAI
RQTMESAGSK YNVLSIGLTN QRETTVAWDS ETGKPLTPAI VWSDARTAAV CKAMSDKVGG
QDGLRAVTGL PVSTYFSAYK LRWMVEHVPA VAAALEAGRL AFGTVDSWVI YNLTGGVKGG
VHITDVTNAS RTSLMDIRSC DWHAETVAAF GFQKVLLPRI VSNAERYGVL ASGPLAGVPL
AGCLGDQQAA VLGQRCALGE AKNTYGTGCF MLMNTGTEAV ASSHGLLTTL AYQLGRDAAP
EYALEGAIAV AGQGVSWLCD SLGLIASPAE SEALAASVPH SGGVYCIPAF GGLLAPWWRP
DARGVIVGLT QYSTKAHVVR AVLESIAFQT LDVLAAMEAD SGHRLRRLAV DGGVTKNRLL
MQVQADLLQC EVVRPANQET TSLGAALAAG IAVGFWTREG LFAQAKGGEG TVVFSPQASP
EWASKRHAKW KLAVQRAMAL DELAESDEEA E
//
