ID A0A087SRA3_AUXPR Unreviewed; 397 AA.
AC A0A087SRA3;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Eukaryotic translation initiation factor 5 {ECO:0000313|EMBL:KFM28257.1};
GN ORFNames=F751_1536 {ECO:0000313|EMBL:KFM28257.1};
OS Auxenochlorella protothecoides (Green microalga) (Chlorella
OS protothecoides).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Chlorellales; Chlorellaceae; Auxenochlorella.
OX NCBI_TaxID=3075 {ECO:0000313|EMBL:KFM28257.1, ECO:0000313|Proteomes:UP000028924};
RN [1] {ECO:0000313|EMBL:KFM28257.1, ECO:0000313|Proteomes:UP000028924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0710 {ECO:0000313|EMBL:KFM28257.1,
RC ECO:0000313|Proteomes:UP000028924};
RX PubMed=25012212; DOI=10.1186/1471-2164-15-582;
RA Gao C., Wang Y., Shen Y., Yan D., He X., Dai J., Wu Q.;
RT "Oil accumulation mechanisms of the oleaginous microalga Chlorella
RT protothecoides revealed through its genome, transcriptomes, and
RT proteomes.";
RL BMC Genomics 15:582-582(2014).
CC -!- SIMILARITY: Belongs to the eIF-2-beta/eIF-5 family.
CC {ECO:0000256|ARBA:ARBA00010397}.
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DR EMBL; KL662166; KFM28257.1; -; Genomic_DNA.
DR RefSeq; XP_011401271.1; XM_011402969.1.
DR AlphaFoldDB; A0A087SRA3; -.
DR STRING; 3075.A0A087SRA3; -.
DR GeneID; 23612927; -.
DR KEGG; apro:F751_1536; -.
DR eggNOG; KOG2767; Eukaryota.
DR OrthoDB; 5475947at2759; -.
DR Proteomes; UP000028924; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.180; -; 1.
DR Gene3D; 2.20.25.350; -; 1.
DR Gene3D; 3.30.30.170; -; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR045196; IF2/IF5.
DR InterPro; IPR002735; Transl_init_fac_IF2/IF5_dom.
DR InterPro; IPR016189; Transl_init_fac_IF2/IF5_N.
DR InterPro; IPR016190; Transl_init_fac_IF2/IF5_Zn-bd.
DR InterPro; IPR003307; W2_domain.
DR PANTHER; PTHR23001; EUKARYOTIC TRANSLATION INITIATION FACTOR; 1.
DR PANTHER; PTHR23001:SF7; EUKARYOTIC TRANSLATION INITIATION FACTOR 5; 1.
DR Pfam; PF01873; eIF-5_eIF-2B; 1.
DR Pfam; PF02020; W2; 1.
DR SMART; SM00653; eIF2B_5; 1.
DR SMART; SM00515; eIF5C; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF100966; Translation initiation factor 2 beta, aIF2beta, N-terminal domain; 1.
DR SUPFAM; SSF75689; Zinc-binding domain of translation initiation factor 2 beta; 1.
DR PROSITE; PS51363; W2; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540,
KW ECO:0000313|EMBL:KFM28257.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000028924}.
FT DOMAIN 226..394
FT /note="W2"
FT /evidence="ECO:0000259|PROSITE:PS51363"
FT REGION 148..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 148..166
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 397 AA; 42093 MW; 8E2162AA1AF71B19 CRC64;
MASINIGGEN AGDAFYRYKM PKLKARIEGR GNGIKTNVEN NVDIAKALER PPEYTLKFFG
CELGAQTKFE KASGTSIVNG AHDASRLSEL LESFIKKYVQ CYSCGNPETV VKIKRENIFL
KCKACGFVSE VDARLKLNTF ILKNPPDNKL SKAEKKSKKE EADASANGDG PEGNLEAEMA
AAKKAEEAAK KAAEEEAAAA AAAQAEADAA AAKKAEEDAR LAEEAAAKLA LASPEVAAMS
TLRQLLASGT APAELAATLR SLELPGGPAA RASALYQVLF GDVEAGAKLS AEVEGRKAYL
APFSKDAAGQ LGQLVAVEKL VGVTLPARVR EAPLVIKALY DLDLVEEDLI LAWYKRADAA
SVLEVPASAA SAVRAASRPF VEWLEQAESS EEDSDEE
//
