ID A0A087V4D2_BALRE Unreviewed; 502 AA.
AC A0A087V4D2;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Neutrophil cytosol factor 2 {ECO:0000313|EMBL:KFO07474.1};
DE Flags: Fragment;
GN ORFNames=N312_07910 {ECO:0000313|EMBL:KFO07474.1};
OS Balearica regulorum gibbericeps (East African grey crowned-crane).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Gruiformes; Gruidae; Balearica.
OX NCBI_TaxID=100784 {ECO:0000313|EMBL:KFO07474.1, ECO:0000313|Proteomes:UP000053309};
RN [1] {ECO:0000313|EMBL:KFO07474.1, ECO:0000313|Proteomes:UP000053309}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N312 {ECO:0000313|EMBL:KFO07474.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the NCF2/NOXA1 family.
CC {ECO:0000256|ARBA:ARBA00008051}.
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DR EMBL; KL479415; KFO07474.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087V4D2; -.
DR Proteomes; UP000053309; Unassembled WGS sequence.
DR GO; GO:0043020; C:NADPH oxidase complex; IEA:InterPro.
DR GO; GO:0016176; F:superoxide-generating NADPH oxidase activator activity; IEA:InterPro.
DR GO; GO:0006909; P:phagocytosis; IEA:InterPro.
DR GO; GO:0045730; P:respiratory burst; IEA:InterPro.
DR CDD; cd12046; SH3_p67phox_C; 1.
DR CDD; cd11871; SH3_p67phox_N; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 2.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR034889; NCF2_SH3.
DR InterPro; IPR035546; p67phox_SH3_1.
DR InterPro; IPR000270; PB1_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR013105; TPR_2.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR15175:SF3; NEUTROPHIL CYTOSOL FACTOR 2; 1.
DR PANTHER; PTHR15175; NEUTROPHIL CYTOSOLIC FACTOR 2, NEUTROPHIL NADPH OXIDASE FACTOR 2; 1.
DR Pfam; PF00564; PB1; 1.
DR Pfam; PF00018; SH3_1; 2.
DR Pfam; PF07719; TPR_2; 1.
DR Pfam; PF13181; TPR_8; 1.
DR PRINTS; PR00499; P67PHOX.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00666; PB1; 1.
DR SMART; SM00326; SH3; 2.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR SUPFAM; SSF50044; SH3-domain; 2.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50002; SH3; 2.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000053309};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 71..104
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 240..299
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 447..502
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 312..332
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 502
FT /evidence="ECO:0000313|EMBL:KFO07474.1"
SQ SEQUENCE 502 AA; 56442 MW; CCBA0E6EAADE1151 CRC64;
MSLVETIRLW QEGVCAADGK EWRAALDAFT AVQNPPAKIC FNIGCIQLVL GKLAEAEEAF
TRSISCDKHL AVAYFQRGTV FYRRQNHEKA IEDFKEALAQ LRGNQLIDYK ILGLRYRLFA
CEILYNIALV YATMEDWKKA EEHLTLAMSM KSEPQHNKID RAMEAILKQK LYELVAIPTG
KLFRPNEKQV AQLEKKDYLG KAMVVASVVD RDDFSGFAPL QPQASGPPPR PKNPEILRAL
EGQPHRVLYE FIPETTEELQ VLPGNIVFVL KKEKDNWATV MFNGKKGIVP CNYLEPVELQ
NKLHIQEEVP LETEIPEPPS STAPEKPRRP VPVCRPQEAE AATSSPRILK VHYKYTVALQ
LEPDLSYAEL LDLVCKKLDL QPEHTQLRYK PAGSQALVAL SAENLEAAWS QSRDNSLTVW
CDIMEGEGVL LDSKPEEAPQ EAAPEETGPT QVVAQYSYEA TQPEDLEFQA GDVILVLSKV
NEDWLEGQCN GKIGIFPSAF VQ
//
