ID   A0A087V951_BALRE        Unreviewed;       789 AA.
AC   A0A087V951;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Neuroligin-3 {ECO:0000313|EMBL:KFO09143.1};
DE   Flags: Fragment;
GN   ORFNames=N312_01737 {ECO:0000313|EMBL:KFO09143.1};
OS   Balearica regulorum gibbericeps (East African grey crowned-crane).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Gruiformes; Gruidae; Balearica.
OX   NCBI_TaxID=100784 {ECO:0000313|EMBL:KFO09143.1, ECO:0000313|Proteomes:UP000053309};
RN   [1] {ECO:0000313|EMBL:KFO09143.1, ECO:0000313|Proteomes:UP000053309}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N312 {ECO:0000313|EMBL:KFO09143.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC       Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC   -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC       {ECO:0000256|ARBA:ARBA00005964}.
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DR   EMBL; KL484474; KFO09143.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A087V951; -.
DR   ESTHER; balpa-a0a087v951; Neuroligin.
DR   Proteomes; UP000053309; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0042043; F:neurexin family protein binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007416; P:synapse assembly; IEA:UniProt.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002018; CarbesteraseB.
DR   InterPro; IPR019819; Carboxylesterase_B_CS.
DR   InterPro; IPR000460; Nlgn.
DR   PANTHER; PTHR43903; NEUROLIGIN; 1.
DR   PANTHER; PTHR43903:SF4; NEUROLIGIN-3; 1.
DR   Pfam; PF00135; COesterase; 1.
DR   PRINTS; PR01090; NEUROLIGIN.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   PROSITE; PS00941; CARBOXYLESTERASE_B_2; 1.
PE   3: Inferred from homology;
KW   Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053309};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        650..673
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          4..567
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
FT   REGION          618..638
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          677..697
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFO09143.1"
FT   NON_TER         789
FT                   /evidence="ECO:0000313|EMBL:KFO09143.1"
SQ   SEQUENCE   789 AA;  87959 MW;  EDED489128A8DE26 CRC64;
     QVYSPTVNTH YGKLRGVRVP LPSEILGPVD QYLGVPYAAP PIGEKRFMPP EPPPSWSGIR
     NATHFSPVCP QNIHNAVPEI MLPIWFTSNL DIVATYIQDP NEDCLYLNIY IPTEDGASAK
     KQGEDLADND GDEDEDIRDS GAKPVMVYIH GGSYMEGTGN MIDGSILASY GNVIVITLNY
     RVGVLGFLST GDQAAKGNYG LLDQIQALRW VSENIAFFGG DPLRITVFGS GIGASCVSLL
     TLSHHSEGLF QRAIIQSGSA LSSWAVNYQP VKYTSMLADK VGCNVLDTVD MVDCLRQKSA
     KELVEQDIQP ARYHVAFGPV IDGDVIPDDP EILMEQGEFL NYDIMLGVNQ GEGLKFVEGV
     VDPEDGVSGS DFDYSVSNFV DNLYGYPEGK DTLRETIKFM YTDWADRDNP ETRRKTLVAL
     FTDHQWVEPS VVTADLHARY GSPTYFYAFY HHCQSLMKPA WSDAAHGDEV PYVFGIPMIG
     PTDLFPCNFS KNDVMLSAVV MTYWTNFAKT GDPNKPVPQD TKFIHTKANR FEEVAWSKYN
     PRDQLYLHIG LKPRVRDHYR ATKVAFWKHL VPHLYNLHDM FHYTSTTTKV PPPDTTQNSH
     ITRRPNGKIW TTKRPAISPA YNSENGKEKW SPEQEAGTLL ESPRDYSTEL SVTIAVGASL
     LFLNVLAFAA LYYRKDKRRQ DTHRQPSPQH GTANDIAHAP DEEMPSLQVS QGHHECEAVP
     PHDTLRLAAL PDYTLTLRRS PDDIPLMTPN TITMIPNSLV GLQTLHPYNT FTAGFNSTGL
     PHSHSTTRV
//