ID   A0A087VAU6_BALRE        Unreviewed;       560 AA.
AC   A0A087VAU6;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Amiloride-sensitive sodium channel subunit alpha {ECO:0000313|EMBL:KFO09738.1};
DE   Flags: Fragment;
GN   ORFNames=N312_12887 {ECO:0000313|EMBL:KFO09738.1};
OS   Balearica regulorum gibbericeps (East African grey crowned-crane).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Gruiformes; Gruidae; Balearica.
OX   NCBI_TaxID=100784 {ECO:0000313|EMBL:KFO09738.1, ECO:0000313|Proteomes:UP000053309};
RN   [1] {ECO:0000313|EMBL:KFO09738.1, ECO:0000313|Proteomes:UP000053309}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N312 {ECO:0000313|EMBL:KFO09738.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; KL486401; KFO09738.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A087VAU6; -.
DR   Proteomes; UP000053309; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015280; F:ligand-gated sodium channel activity; IEA:InterPro.
DR   Gene3D; 2.60.470.10; Acid-sensing ion channels like domains; 1.
DR   Gene3D; 1.10.287.770; YojJ-like; 1.
DR   InterPro; IPR001873; ENaC.
DR   InterPro; IPR004724; ENaC_chordates.
DR   InterPro; IPR020903; ENaC_CS.
DR   NCBIfam; TIGR00859; ENaC; 1.
DR   PANTHER; PTHR11690:SF132; AMILORIDE-SENSITIVE SODIUM CHANNEL SUBUNIT DELTA; 1.
DR   PANTHER; PTHR11690; AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED; 1.
DR   Pfam; PF00858; ASC; 1.
DR   PRINTS; PR01078; AMINACHANNEL.
DR   PROSITE; PS01206; ASC; 1.
PE   4: Predicted;
KW   Ion channel {ECO:0000313|EMBL:KFO09738.1};
KW   Ion transport {ECO:0000256|ARBA:ARBA00022461};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053309};
KW   Sodium {ECO:0000256|ARBA:ARBA00023053};
KW   Sodium channel {ECO:0000256|ARBA:ARBA00022461};
KW   Sodium transport {ECO:0000256|ARBA:ARBA00023201};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022461}.
FT   TRANSMEM        49..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFO09738.1"
FT   NON_TER         560
FT                   /evidence="ECO:0000313|EMBL:KFO09738.1"
SQ   SEQUENCE   560 AA;  64558 MW;  A3E9D0E499B52B24 CRC64;
     EEEKKEGLIE FYDSFKDMFE FFCKNTTIHG TIRLVCSDSN RMKTAFWTLL LLASFGMLYW
     QFALMFSQYW AYPVVLTMSM HSEPKMFPAI TICNLDPYRF ELVSEHLVQL DRMAEESITF
     LYGINTSASL FHMNEKNIHI KDFSNIGNLS RSSFKLSQNF SLLRMSDHSN RSGKKHSSVG
     FRLCNATGGN CFYKTYSSGM DAILEWYRFH YVNIMSQLPV IINISDHEEQ IEDMVYSCQY
     DGEPCRPSDY VHFHHPVFGS CYTFNSKGTD PFWTATKPGI PYGLSLILRA EQKDHIPLLS
     TVAGVKVMIH NHNQTPFLEH EGFDIRPGIA TTIGIQQDEV NRLGGNYGKC TTNGNDVNVK
     LLYNNSYTLQ ACLHFCFQHI MVQKCGCGYY YYPLPPGAEY CNYNKQPAWG HCFYQLYNRL
     RNHHLNCFDQ CPKPCRESLY KVSAGTAKWP SSKSQDWIRQ ALRHQNGYNS TSNRKDIAKV
     TIFYQQLNYQ SVNESPLLSE NLLLSSMGSQ WSLWFGSSVL SVVEMFELLV DTLVLSLLFC
     YQRLRSKKTL KVAHTPTIPS
//