ID A0A087VCR4_BALRE Unreviewed; 488 AA.
AC A0A087VCR4;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Aldehyde dehydrogenase family 8 member A1 {ECO:0000313|EMBL:KFO10406.1};
DE Flags: Fragment;
GN ORFNames=N312_13633 {ECO:0000313|EMBL:KFO10406.1};
OS Balearica regulorum gibbericeps (East African grey crowned-crane).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Gruiformes; Gruidae; Balearica.
OX NCBI_TaxID=100784 {ECO:0000313|EMBL:KFO10406.1, ECO:0000313|Proteomes:UP000053309};
RN [1] {ECO:0000313|EMBL:KFO10406.1, ECO:0000313|Proteomes:UP000053309}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N312 {ECO:0000313|EMBL:KFO10406.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
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DR EMBL; KL488450; KFO10406.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087VCR4; -.
DR Proteomes; UP000053309; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd07093; ALDH_F8_HMSADH; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR43720; 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43720:SF2; 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000053309}.
FT DOMAIN 25..484
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 254
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO10406.1"
FT NON_TER 488
FT /evidence="ECO:0000313|EMBL:KFO10406.1"
SQ SEQUENCE 488 AA; 53204 MW; 1D29B2BC1DD16DF8 CRC64;
TMAHSKALLV LENFIAGKFV PCSSYLNSYN PSTGDVYCRV PDSGKEEVEA AVKAAKAAFP
IWSSKSLLER SQILNKLADL IEHDLEAFAQ AESKDQGKTI TFARTVDIPR AVYNFRFFAS
SILHHTTECT EMATMGCVHY TSRAPVGVAG LISPWNLPLY LLTWKIAPAI ACGNTVVAKP
SEMTSVTAWM MCKLLEKAGV PHGVVNVVFG TGAKAGEALV CHPDVPLISF TGSTLTAQRI
TEKSAPHCKR LSLELGGKNP AIIFDDADLS QCIPTTLRSS FANQGEICLC TSRIFVQRGI
YSEFLKRFVA EAKKWKVGNP SDPTVDMGAL ISKEHLEKVR SYVKKAQGEG AKVLCGEGVD
SLALPTGNQK GYFMLPTIIA EVKDESCCMQ EEIFGPVTCV VAFDTEEEVI KRANSVKYGL
AATVWSSNVG RVHRVAQRLQ SGLVWTNCWL VRDLNLPFGG MKASGIGREG AKDSYEFFTE
VKTITIKH
//
