ID A0A087VJY6_BALRE Unreviewed; 226 AA.
AC A0A087VJY6;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Ectodysplasin-A {ECO:0000313|EMBL:KFO12928.1};
DE Flags: Fragment;
GN ORFNames=N312_07938 {ECO:0000313|EMBL:KFO12928.1};
OS Balearica regulorum gibbericeps (East African grey crowned-crane).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Gruiformes; Gruidae; Balearica.
OX NCBI_TaxID=100784 {ECO:0000313|EMBL:KFO12928.1, ECO:0000313|Proteomes:UP000053309};
RN [1] {ECO:0000313|EMBL:KFO12928.1, ECO:0000313|Proteomes:UP000053309}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N312 {ECO:0000313|EMBL:KFO12928.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the tumor necrosis factor family.
CC {ECO:0000256|ARBA:ARBA00008670}.
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DR EMBL; KL496159; KFO12928.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087VJY6; -.
DR Proteomes; UP000053309; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005164; F:tumor necrosis factor receptor binding; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR Gene3D; 2.60.120.40; -; 1.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR006052; TNF_dom.
DR InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR PANTHER; PTHR15151:SF13; ECTODYSPLASIN-A; 1.
DR PANTHER; PTHR15151; PROTEIN EIGER; 1.
DR Pfam; PF01391; Collagen; 1.
DR Pfam; PF00229; TNF; 1.
DR SUPFAM; SSF49842; TNF-like; 1.
DR PROSITE; PS50049; TNF_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000053309}.
FT DOMAIN 85..220
FT /note="TNF family profile"
FT /evidence="ECO:0000259|PROSITE:PS50049"
FT REGION 1..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..65
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO12928.1"
FT NON_TER 226
FT /evidence="ECO:0000313|EMBL:KFO12928.1"
SQ SEQUENCE 226 AA; 23550 MW; 5EB5DD89835CA1DC CRC64;
GPSSVKNKKK GKKAGPPGPN GPQGPPGPPG PQGPPGIPGI PGIPGTTVMG PPGPPGPPGP
QGPPGLQGPS GATDKAGSRD IQPAVVHLQG QGSAIQVKND LSGGVLNDWS RITMNPKVFK
LHARSGELEV LVDGTYFIYS QVEVYYINFT DFASYEVVVD EKPFLQCTRS IETGKTNFNT
CYTAGVCLLK ARQKIAVKMV HADISINMSK HTTFFGAIRL GDAPAS
//
