ID A0A087VPE3_BALRE Unreviewed; 403 AA.
AC A0A087VPE3;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Calpain-7 {ECO:0000313|EMBL:KFO14485.1};
DE Flags: Fragment;
GN ORFNames=N312_04281 {ECO:0000313|EMBL:KFO14485.1};
OS Balearica regulorum gibbericeps (East African grey crowned-crane).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Gruiformes; Gruidae; Balearica.
OX NCBI_TaxID=100784 {ECO:0000313|EMBL:KFO14485.1, ECO:0000313|Proteomes:UP000053309};
RN [1] {ECO:0000313|EMBL:KFO14485.1, ECO:0000313|Proteomes:UP000053309}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N312 {ECO:0000313|EMBL:KFO14485.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C2 family.
CC {ECO:0000256|ARBA:ARBA00007623}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00239}.
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DR EMBL; KL500688; KFO14485.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087VPE3; -.
DR MEROPS; C02.029; -.
DR Proteomes; UP000053309; Unassembled WGS sequence.
DR GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 1.20.58.80; Phosphotransferase system, lactose/cellobiose-type IIA subunit; 1.
DR InterPro; IPR022684; Calpain_cysteine_protease.
DR InterPro; IPR007330; MIT_dom.
DR InterPro; IPR036181; MIT_dom_sf.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR001300; Peptidase_C2_calpain_cat.
DR PANTHER; PTHR46143; CALPAIN-7; 1.
DR PANTHER; PTHR46143:SF1; CALPAIN-7; 1.
DR Pfam; PF04212; MIT; 1.
DR Pfam; PF00648; Peptidase_C2; 1.
DR PRINTS; PR00704; CALPAIN.
DR SMART; SM00230; CysPc; 1.
DR SMART; SM00745; MIT; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF116846; MIT domain; 1.
DR PROSITE; PS50203; CALPAIN_CAT; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000053309}.
FT DOMAIN 233..403
FT /note="Calpain catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50203"
FT REGION 120..144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 265
FT /evidence="ECO:0000256|PIRSR:PIRSR622684-1"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO14485.1"
FT NON_TER 403
FT /evidence="ECO:0000313|EMBL:KFO14485.1"
SQ SEQUENCE 403 AA; 45439 MW; 1D4717B8586F81EC CRC64;
FSLQEAAQAL IYAGMAGSNL ENIQEKINEY LERVQALHSA VQSQNTDPLK SKQQLDLERA
HFLVTQAFDE DDKGNAEEAI ELYTEAVELC LKTATETSEA GLQSKLKQLA RQALDRAEAL
KESVSKSSQK EKSTSAKPNQ PVRTFFPLGP DFSLNDKPQT IRAVQASESQ GQRYTAEEIE
VLRQVEDKKT SKINGIEYVP FMSVDLRERF AFPMPFSDKC GKLPLSPKQK AMFAKWVRPD
DITNNPTMIY TVSSFSIKQT IVSDCSFVAS LAISAAYERR YNKKLITSII YPQNKKGEPE
YNPCGKHMVK LHINGVPRKV IIDDQLPVDH SGELLCSYSN NKNELWVSLI EKAYMKVMGG
YDFPGSNSNI DLHALTGWIP ERIAMHSDNQ AFNKDSTFRM LYQ
//
