ID A0A087VSE4_9BIFI Unreviewed; 406 AA.
AC A0A087VSE4;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE RecName: Full=DNA replication and repair protein RecF {ECO:0000256|HAMAP-Rule:MF_00365};
GN Name=recF {ECO:0000256|HAMAP-Rule:MF_00365};
GN ORFNames=BINDI_1369 {ECO:0000313|EMBL:AIC91272.1};
OS Bifidobacterium indicum LMG 11587 = DSM 20214.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=1341694 {ECO:0000313|EMBL:AIC91272.1, ECO:0000313|Proteomes:UP000028569};
RN [1] {ECO:0000313|EMBL:AIC91272.1, ECO:0000313|Proteomes:UP000028569}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 11587 {ECO:0000313|EMBL:AIC91272.1,
RC ECO:0000313|Proteomes:UP000028569};
RX PubMed=25085493; DOI=10.1128/AEM.02308-14;
RA Milani C., Lugli G.A., Duranti S., Turroni F., Bottacini F., Mangifesta M.,
RA Sanchez B., Viappiani A., Mancabelli L., Taminiau B., Delcenserie V.,
RA Barrangou R., Margolles A., van Sinderen D., Ventura M.;
RT "Genomic encyclopedia of type strains of the genus Bifidobacterium.";
RL Appl. Environ. Microbiol. 80:6290-6302(2014).
CC -!- FUNCTION: The RecF protein is involved in DNA metabolism; it is
CC required for DNA replication and normal SOS inducibility. RecF binds
CC preferentially to single-stranded, linear DNA. It also seems to bind
CC ATP. {ECO:0000256|ARBA:ARBA00025401, ECO:0000256|HAMAP-Rule:MF_00365}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00365}.
CC -!- SIMILARITY: Belongs to the RecF family. {ECO:0000256|HAMAP-
CC Rule:MF_00365}.
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DR EMBL; CP006018; AIC91272.1; -; Genomic_DNA.
DR RefSeq; WP_033491029.1; NZ_JDUE01000002.1.
DR AlphaFoldDB; A0A087VSE4; -.
DR KEGG; bii:BINDI_1369; -.
DR HOGENOM; CLU_040267_1_1_11; -.
DR OrthoDB; 9803889at2; -.
DR Proteomes; UP000028569; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.1050.90; RecF/RecN/SMC, N-terminal domain; 1.
DR HAMAP; MF_00365; RecF; 1.
DR InterPro; IPR001238; DNA-binding_RecF.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR042174; RecF_2.
DR NCBIfam; TIGR00611; recf; 1.
DR PANTHER; PTHR32182; DNA REPLICATION AND REPAIR PROTEIN RECF; 1.
DR PANTHER; PTHR32182:SF0; DNA REPLICATION AND REPAIR PROTEIN RECF; 1.
DR Pfam; PF02463; SMC_N; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_00365};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_00365};
KW DNA damage {ECO:0000256|HAMAP-Rule:MF_00365};
KW DNA repair {ECO:0000256|HAMAP-Rule:MF_00365};
KW DNA replication {ECO:0000256|HAMAP-Rule:MF_00365};
KW DNA-binding {ECO:0000256|HAMAP-Rule:MF_00365};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_00365}; Reference proteome {ECO:0000313|Proteomes:UP000028569};
KW SOS response {ECO:0000256|HAMAP-Rule:MF_00365}.
FT DOMAIN 2..357
FT /note="RecF/RecN/SMC N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02463"
FT BINDING 30..37
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00365"
SQ SEQUENCE 406 AA; 44462 MW; B33785B7AD61DA6F CRC64;
MYISRLVLDH YRSWSTCLLD LEPGVTILKG RNGLGKTNLV EAIEVLSTGT SHRVSSSLPL
VERGQSKATV RARVQGDGES DDYELTIAAK GAKRGRINGG PSLYMRSLVG QVPCVTFSPE
DQRMVSGEPS VRRAFLDQAG ALLDPDYFRS RQDFAHIAQQ RSTLLRQLLK QGDQGADQRN
AILASLEIWT GQFIRAGLDL TRRRVGLVAA LAEPFRALYA DLAGPGQEAS LDYAPSLDEI
SNQTVSEGSV EEAVSLHFQR IYPGEVARGT NLIGPQRDDL VFGLNGMPAR EFASNGEMWT
LALALRLALF KVIIQSKQIR PIVVLDDVFA QLDEARRSQI LAFARDQDQV LITAAADGDI
PSLDGARLVD VDSLKTDSSE QEQDEEIRKA LADLTRNGSV RESGRS
//
