ID A0A087VXQ4_ECHMU Unreviewed; 1793 AA.
AC A0A087VXQ4;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 22-FEB-2023, entry version 27.
DE SubName: Full=Fanconi anemia group D2 protein {ECO:0000313|EMBL:CDI96998.1};
GN ORFNames=EmuJ_000074000 {ECO:0000313|EMBL:CDI96998.1};
OS Echinococcus multilocularis (Fox tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus.
OX NCBI_TaxID=6211 {ECO:0000313|EMBL:CDI96998.1};
RN [1] {ECO:0000313|EMBL:CDI96998.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23485966; DOI=10.1038/nature12031;
RA Tsai I.J., Zarowiecki M., Holroyd N., Garciarrubio A., Sanchez-Flores A.,
RA Brooks K.L., Tracey A., Bobes R.J., Fragoso G., Sciutto E., Aslett M.,
RA Beasley H., Bennett H.M., Cai J., Camicia F., Clark R., Cucher M.,
RA De Silva N., Day T.A., Deplazes P., Estrada K., Fernandez C., Holland P.W.,
RA Hou J., Hu S., Huckvale T., Hung S.S., Kamenetzky L., Keane J.A., Kiss F.,
RA Koziol U., Lambert O., Liu K., Luo X., Luo Y., Macchiaroli N., Nichol S.,
RA Paps J., Parkinson J., Pouchkina-Stantcheva N., Riddiford N., Rosenzvit M.,
RA Salinas G., Wasmuth J.D., Zamanian M., Zheng Y., Cai X., Soberon X.,
RA Olson P.D., Laclette J.P., Brehm K., Berriman M., Garciarrubio A.,
RA Bobes R.J., Fragoso G., Sanchez-Flores A., Estrada K., Cevallos M.A.,
RA Morett E., Gonzalez V., Portillo T., Ochoa-Leyva A., Jose M.V., Sciutto E.,
RA Landa A., Jimenez L., Valdes V., Carrero J.C., Larralde C.,
RA Morales-Montor J., Limon-Lason J., Soberon X., Laclette J.P.;
RT "The genomes of four tapeworm species reveal adaptations to parasitism.";
RL Nature 496:57-63(2013).
RN [2] {ECO:0000313|EMBL:CDI96998.1}
RP NUCLEOTIDE SEQUENCE.
RA Zhang Y., Guo Z.;
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LN902843; CDI96998.1; -; Genomic_DNA.
DR STRING; 6211.A0A087VXQ4; -.
DR eggNOG; KOG4712; Eukaryota.
DR OMA; WHIANTA; -.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR InterPro; IPR029448; FANCD2.
DR PANTHER; PTHR32086; FANCONI ANEMIA GROUP D2 PROTEIN; 1.
DR PANTHER; PTHR32086:SF0; FANCONI ANEMIA GROUP D2 PROTEIN; 1.
DR Pfam; PF14631; FancD2; 2.
PE 4: Predicted;
FT REGION 679..707
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1045..1114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1729..1793
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 679..697
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1050..1067
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1068..1088
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1089..1104
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1733..1760
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1765..1793
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1793 AA; 198255 MW; 8112071CB0FE79E9 CRC64;
MSADDDIFAE GIRSATMGQN HIPSKFSSIN RSLKIMDIKG AVDQSCLVFF SPGHQSRTSW
HIANTASSRT KALASELSAD AVFRDNLVKE LREIFLTSQF EFDCSILLSP LLTKDSSISD
ELDDLINEED QSDVLMLFGS PASAFQLFLS IPCIQPALLD LLFKVVLSGS NYSLQLISQL
LRPVGISTFF TTFTSLEEVV SRLIEIIKSV DGQTAKTHIL QVLPELVASP VENPQRDLNS
EVVSNTIQKI IELLDYAIFS RSEDQANHTL VTEIIKCANH FPLEGFSLNR LKDACKDVII
RSAEKLSNRK CIADVIRSLF ASELKKCFSL DEICEFVSLL RSKMRLSEIT IGSDQEILLF
LDTLSLVFRS NSQLKLEWLS YLHRGYSNSG VDCGLLIDDL LILLLVYDSE MALGGKFGST
TLNKRKEYSL ILKTFNFVAE RITNREIHES FSKYSAIFQH KQLCGPLLTL TNHLMKTCQF
PAAPRFAYLV YSSIFQSSLP GTEQPKRVIT DLCKNIYSSP TSVSIFEKKR MVRNSKLTIN
LLLQLSSVFA EKMSPFYDQL LGLLEEVSKR AEESPPDLID IRKLFAIPAK IAFGGTGETY
LQDDLLISIR RLLLNCSSKL RAIGLIGAVT VLEMLCKRLK TSKSPGPVNS TPCSQAEVME
CSQSSVLASQ VAIPLASQTT ASQNTTSRSS HSHLSLKGPG TSLADDSEEV NLPADSVDLD
SDPKSASSYL AFLPQPSRLM LQLVGLVENA LRRSSLLFSQ LKVFWYDELA TMFARLEAGC
QRPLLSPESE MKRFIDWMGS RVMREFQEEF VVDNAGNRDC TIQLGLNDAE ICEIALNLGP
TFARHTEATV ALAARPPLSS VAREHITRKP SAANTPFNRS APASPALVPA HLRLLAVVET
FKSNRCLDSM NALLGCPILL PTVPLNDFPP SIIIIIINCC IEAVNTFAEA IVFPSSRHSH
PRRLLSHPLA STLICRLIQI ASLRCCLHAV LLRRVKNAVL TASAAEVPSP IYEAIDTMTF
DPTFVYVTAG HPISAKRFPI FVPSGGKKST VSKCRKRPSR EAKGRPRKRV CTKSLLDATE
HDENEDGGAA TVYDEDEEEE ENGEGANPTT MSLEGGEVLE QTAAVNRLAS VNGSGKSNAL
LSDPLLPSLT VCFRELDLST ILLGLQSPLQ QPADFCWTDE SSLPDSPLDA AVDVIYDVSG
VKHFGRKKSP DTPLNWITIC YLLNELKLKV DHVFGVDLKS SAGWYAFERL DAMSPQLRHS
YLLAVVPGLV RIVNSLTRHF EECRDEDCEN DPFGLSRLSF TPSTRILADC LSTSLYCITA
LSTGILPVVS ALRSPDTLLS KTSPPSDATC LSRLRRLAQC LDNLDISESS LFDNYHLPTV
SMLEDDVLGL ATDPSNQPEA ENEKPSAAEV LRIIQWLMGF SPQGLAHTPS AFIHACFVLS
LARHLNIHVP ATESAINAHS NLLDYTHSLM SMAWETTAGW QAYSHKDCLG TLIALHLYSP
FFGPSPSPLN ECLEVLINLI KFNLLPLLQG RDRDNSDISR QGRLCYSGLT TQSAGLYGRK
VLEAFCFCVR KLAKKTIATA ASRSVDLLNQ WSACLGVLVR ITEATKSDTP SRAFFDLLPY
LMRAGRMFVE HLLRGAMPFL NAMFRSHGSE VLKFLRSVQQ VTRFLQRTCV HAKTRREARL
TPLIPQTRKC LEAFVYSVKL LLAQNHCADA FWLGNLKNRD LAGQEIHDTD VSTRHSSGTT
LSTASPHSSC KGNSKDSSYT VEGAEDLISE DESEVEEEEL PIEDSEEEDK DEN
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