ID A0A087VYD3_ECHMU Unreviewed; 692 AA.
AC A0A087VYD3;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Tom1 protein 2 {ECO:0000313|EMBL:CDI97119.1};
GN ORFNames=EmuJ_000087600 {ECO:0000313|EMBL:CDI97119.1};
OS Echinococcus multilocularis (Fox tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus.
OX NCBI_TaxID=6211 {ECO:0000313|EMBL:CDI97119.1};
RN [1] {ECO:0000313|EMBL:CDI97119.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23485966; DOI=10.1038/nature12031;
RA Tsai I.J., Zarowiecki M., Holroyd N., Garciarrubio A., Sanchez-Flores A.,
RA Brooks K.L., Tracey A., Bobes R.J., Fragoso G., Sciutto E., Aslett M.,
RA Beasley H., Bennett H.M., Cai J., Camicia F., Clark R., Cucher M.,
RA De Silva N., Day T.A., Deplazes P., Estrada K., Fernandez C., Holland P.W.,
RA Hou J., Hu S., Huckvale T., Hung S.S., Kamenetzky L., Keane J.A., Kiss F.,
RA Koziol U., Lambert O., Liu K., Luo X., Luo Y., Macchiaroli N., Nichol S.,
RA Paps J., Parkinson J., Pouchkina-Stantcheva N., Riddiford N., Rosenzvit M.,
RA Salinas G., Wasmuth J.D., Zamanian M., Zheng Y., Cai X., Soberon X.,
RA Olson P.D., Laclette J.P., Brehm K., Berriman M., Garciarrubio A.,
RA Bobes R.J., Fragoso G., Sanchez-Flores A., Estrada K., Cevallos M.A.,
RA Morett E., Gonzalez V., Portillo T., Ochoa-Leyva A., Jose M.V., Sciutto E.,
RA Landa A., Jimenez L., Valdes V., Carrero J.C., Larralde C.,
RA Morales-Montor J., Limon-Lason J., Soberon X., Laclette J.P.;
RT "The genomes of four tapeworm species reveal adaptations to parasitism.";
RL Nature 496:57-63(2013).
RN [2] {ECO:0000313|EMBL:CDI97119.1}
RP NUCLEOTIDE SEQUENCE.
RA Zhang Y., Guo Z.;
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LN902846; CDI97119.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087VYD3; -.
DR STRING; 6211.A0A087VYD3; -.
DR eggNOG; KOG1087; Eukaryota.
DR OMA; NSAFQRY; -.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd14233; GAT_TOM1_like; 1.
DR CDD; cd03565; VHS_Tom1_like; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR13856:SF137; GH05942P; 1.
DR PANTHER; PTHR13856; VHS DOMAIN CONTAINING PROTEIN FAMILY; 1.
DR Pfam; PF03127; GAT; 1.
DR Pfam; PF00790; VHS; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50179; VHS; 1.
PE 4: Predicted;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 21..154
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 373..461
FT /note="GAT"
FT /evidence="ECO:0000259|PROSITE:PS50909"
FT REGION 156..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 218..271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 307..357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 519..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 634..679
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 162..186
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..252
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 318..357
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 640..668
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 692 AA; 77263 MW; F3B700BC93191B40 CRC64;
MQNLFQSHPY STRVGTLIER VTDSGKLAID WTIVLEICDA LGETDEGPKE AIRAIRKRLT
SSAGKDHISI WYTLILIEAC LKNCGRRFQA QVANRDFLHD LIKVLLPKHN PPIQLQTKIL
FLIKSWVDAS WDVPGRRDLE KVYTALRRKG VQFPTPIECK TLPPPQQSST MKRPVSSSAT
SRSTKLASTF RRLTSGALGG GGDCRFKTHL SSLSQNRADD SRRCHYHQQQ SSSTSHLQRV
GTSESPVTNR ARESGRQIRI RNGGGSGIGG IEPGAQVLQV VAINGYPVVT RSGQEVFFAT
APRTFLNHHH HHHQQQQQQQ QQHRYQHQQY ESSQQLQQAS STTHHSMPSG MYSLSGDQTL
VDHEGTVRRL STAQRERLSQ DLTVVQTNLH ILNDMLTELQ PDAISPDDLE LLQELNETCR
MMQQRVAEFL SQVADDAVTL TLIQLNDELN SAFQRYERFE RYRLRALRAQ IANRDVGQSR
AALPSTEMVS SQQLQLEPLM TQPHQQQLQQ RHHINLSLPS TAGMLPHSKD EYEGGGGDNE
EDEDDDDDEL LDAVAEQTQR NPPTTELGDS ELVSVGDWSD NALALQALRL NDTSHTSWNT
DSSAAQLDRV FGEGYNSPIS HPTGTQTAMS TVQVLPGPQL EPLQPQPAPL PTPPAPPPPP
PPSLKALPQP PIKKRTPSEV RRLEEALLLF ES
//
