ID A0A087VZS4_ECHMU Unreviewed; 307 AA.
AC A0A087VZS4;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Pre mRNA splicing regulator female lethal2D {ECO:0000313|EMBL:CDI97882.1};
GN ORFNames=EmuJ_000169100 {ECO:0000313|EMBL:CDI97882.1};
OS Echinococcus multilocularis (Fox tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus.
OX NCBI_TaxID=6211 {ECO:0000313|EMBL:CDI97882.1};
RN [1] {ECO:0000313|EMBL:CDI97882.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23485966; DOI=10.1038/nature12031;
RA Tsai I.J., Zarowiecki M., Holroyd N., Garciarrubio A., Sanchez-Flores A.,
RA Brooks K.L., Tracey A., Bobes R.J., Fragoso G., Sciutto E., Aslett M.,
RA Beasley H., Bennett H.M., Cai J., Camicia F., Clark R., Cucher M.,
RA De Silva N., Day T.A., Deplazes P., Estrada K., Fernandez C., Holland P.W.,
RA Hou J., Hu S., Huckvale T., Hung S.S., Kamenetzky L., Keane J.A., Kiss F.,
RA Koziol U., Lambert O., Liu K., Luo X., Luo Y., Macchiaroli N., Nichol S.,
RA Paps J., Parkinson J., Pouchkina-Stantcheva N., Riddiford N., Rosenzvit M.,
RA Salinas G., Wasmuth J.D., Zamanian M., Zheng Y., Cai X., Soberon X.,
RA Olson P.D., Laclette J.P., Brehm K., Berriman M., Garciarrubio A.,
RA Bobes R.J., Fragoso G., Sanchez-Flores A., Estrada K., Cevallos M.A.,
RA Morett E., Gonzalez V., Portillo T., Ochoa-Leyva A., Jose M.V., Sciutto E.,
RA Landa A., Jimenez L., Valdes V., Carrero J.C., Larralde C.,
RA Morales-Montor J., Limon-Lason J., Soberon X., Laclette J.P.;
RT "The genomes of four tapeworm species reveal adaptations to parasitism.";
RL Nature 496:57-63(2013).
RN [2] {ECO:0000313|EMBL:CDI97882.1}
RP NUCLEOTIDE SEQUENCE.
RA Zhang Y., Guo Z.;
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the fl(2)d family.
CC {ECO:0000256|ARBA:ARBA00010313}.
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DR EMBL; LN902846; CDI97882.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087VZS4; -.
DR STRING; 6211.A0A087VZS4; -.
DR eggNOG; KOG2991; Eukaryota.
DR OMA; LCIREYM; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0080009; P:mRNA methylation; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IEA:InterPro.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR InterPro; IPR033757; WTAP.
DR PANTHER; PTHR15217:SF0; PRE-MRNA-SPLICING REGULATOR WTAP; 1.
DR PANTHER; PTHR15217; WILMS' TUMOR 1-ASSOCIATING PROTEIN; 1.
DR Pfam; PF17098; Wtap; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT REGION 260..307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 5..43
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 288..307
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 307 AA; 34320 MW; A0536EE016758701 CRC64;
MELLAEEQTI TIKQLELKLK KIEEENERLI EKQKAQEEDL SRREADVIRR FLVSNVRLAH
VLSVLPSKLR RKSSDSEFDY DGADDPADEY GEAVGSVKVK ELTHRLNVID PAIDFVYQKA
CEAAQSGKMR LQQSYDDLIA WKFTPDSASG KRLMACMRKL LEQNKHLGAI NQMDRLAALE
SETQVQVSCI LEYMKTAQEL NAVLQESSTD LDGVQSSLFT LKKQLNKAEA LVNVLKEEYE
KVNPGQSDSL ITAALTRLSQ QAMAAESENT ETEEVEGGEP REDGEAQPLV ESTSSTATTE
ASSHEPK
//
