ID A0A087WNM9_MOUSE Unreviewed; 745 AA.
AC A0A087WNM9;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Kirre like nephrin family adhesion molecule 3 {ECO:0000313|Ensembl:ENSMUSP00000139418.2};
GN Name=Kirrel3 {ECO:0000313|Ensembl:ENSMUSP00000139418.2,
GN ECO:0000313|MGI:MGI:1914953};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000139418.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000139418.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000139418.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000139418.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000139418.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily.
CC {ECO:0000256|ARBA:ARBA00008637}.
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DR AlphaFoldDB; A0A087WNM9; -.
DR SMR; A0A087WNM9; -.
DR ProteomicsDB; 310690; -.
DR Antibodypedia; 33010; 180 antibodies from 30 providers.
DR Ensembl; ENSMUST00000188933.7; ENSMUSP00000139418.2; ENSMUSG00000032036.16.
DR AGR; MGI:1914953; -.
DR MGI; MGI:1914953; Kirrel3.
DR VEuPathDB; HostDB:ENSMUSG00000032036; -.
DR GeneTree; ENSGT00940000157126; -.
DR ChiTaRS; Kirrel3; mouse.
DR Proteomes; UP000000589; Chromosome 9.
DR Bgee; ENSMUSG00000032036; Expressed in cortical plate and 153 other cell types or tissues.
DR ExpressionAtlas; A0A087WNM9; baseline and differential.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR CDD; cd05759; IgI_2_KIRREL3-like; 1.
DR CDD; cd05898; IgI_5_KIRREL3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR11640:SF49; KIN OF IRRE-LIKE PROTEIN 3; 1.
DR PANTHER; PTHR11640; NEPHRIN; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF07679; I-set; 2.
DR Pfam; PF13927; Ig_3; 1.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 1: Evidence at protein level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Proteomics identification {ECO:0007829|MaxQB:A0A087WNM9,
KW ECO:0007829|ProteomicsDB:A0A087WNM9};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 499..525
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 15..109
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 114..210
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 216..297
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 302..382
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 386..482
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 694..745
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 745 AA; 81523 MW; 80D9A636F042EB3E CRC64;
MAKDKFRRMN EGQVYSFSQQ PQDQVVVSGQ PVTLLCAIPE YDGFVLWIKD GLALGVGRDL
SSYPQYLVVG NHLSGEHHLK ILRAELQDDA VYECQAIQAA IRSRPARLTV LVPPDDPIIL
GGPVISLRAG DPLNLTCHAD NAKPAASIIW LRKGEVINGA TYSKTLLRDG KRESIVSTLF
ISPGDVENGQ SIVCRATNKA IPGGKETSVT IDIQHPPLVN LSVEPQPVLE DNIVTFHCSA
KANPAVTQYR WAKRGHIIKE ASGELYRTTV DYTYFSEPVS CEVTNALGST NLSRTVDVYF
GPRMTSEPQS LLVDLGSDAV FSCAWIGNPS LTIVWMKRGS GVVLSNEKTL TLKSVRQEDA
GKYVCRAVVP RVGAGEREVT LTVNGPPIIS STQTQHALHG EKGQIKCFIR STPPPDRIAW
SWKENVLESG TSGRYTVETV NTEEGVISTL TISNIVRADF QTIYNCTAWN SFGSDTEIIR
LKEQGSEMKS GAGLEAESVP MAVIIGVAVG AGVAFLVLMA TIVAFCCARS QRNLKGVVSA
KNDIRVEIVH KEPSSGREAE DHTTIKQLMM DRGEFQQDSV LKQLEVLKEE EKEFQNLKDP
TNGYYSVNTF KEHHSTPTIS LSSCQPDLRP TGKQRVPTGM SFTNIYSTLS GQGRLYDYGQ
RFVLGMGSSS IELCEREFQR GSLSDSSSFL DTQCDSSVSS SGKQDGYVQF DKASKASASS
SHHSQSSSQN SDPSRPLQRR MQTHV
//
