ID A0A087WS02_MOUSE Unreviewed; 185 AA.
AC A0A087WS02;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Phosducin {ECO:0000256|ARBA:ARBA00040013};
DE Flags: Fragment;
GN Name=Pdc {ECO:0000313|Ensembl:ENSMUSP00000140843.2,
GN ECO:0000313|MGI:MGI:98090};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000140843.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000140843.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000140843.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000140843.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000140843.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium, photoreceptor outer
CC segment {ECO:0000256|ARBA:ARBA00004504}. Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}. Photoreceptor inner segment
CC {ECO:0000256|ARBA:ARBA00004437}.
CC -!- SIMILARITY: Belongs to the phosducin family.
CC {ECO:0000256|ARBA:ARBA00009686}.
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DR AlphaFoldDB; A0A087WS02; -.
DR SMR; A0A087WS02; -.
DR ProteomicsDB; 353013; -.
DR Antibodypedia; 34456; 121 antibodies from 20 providers.
DR Ensembl; ENSMUST00000186572.7; ENSMUSP00000140843.2; ENSMUSG00000006007.15.
DR AGR; MGI:98090; -.
DR MGI; MGI:98090; Pdc.
DR VEuPathDB; HostDB:ENSMUSG00000006007; -.
DR GeneTree; ENSGT00940000156236; -.
DR HOGENOM; CLU_085598_1_0_1; -.
DR OMA; PKYGYLC; -.
DR ChiTaRS; Pdc; mouse.
DR Proteomes; UP000000589; Chromosome 1.
DR Bgee; ENSMUSG00000006007; Expressed in retinal neural layer and 59 other cell types or tissues.
DR ExpressionAtlas; A0A087WS02; baseline and differential.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0001917; C:photoreceptor inner segment; IEA:UniProtKB-SubCell.
DR GO; GO:0001750; C:photoreceptor outer segment; IEA:UniProtKB-SubCell.
DR GO; GO:0008277; P:regulation of G protein-coupled receptor signaling pathway; IEA:InterPro.
DR GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
DR CDD; cd02987; Phd_like_Phd; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 1.10.168.10; Phosducin, domain 2; 2.
DR InterPro; IPR001200; Phosducin.
DR InterPro; IPR023196; Phosducin_N_dom_sf.
DR InterPro; IPR024253; Phosducin_thioredoxin-like_dom.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR46052:SF3; PHOSDUCIN; 1.
DR PANTHER; PTHR46052; PHOSDUCIN-LIKE PROTEIN; 1.
DR Pfam; PF02114; Phosducin; 1.
DR PRINTS; PR00677; PHOSDUCIN.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
PE 1: Evidence at protein level;
KW Cell projection {ECO:0000256|ARBA:ARBA00023069};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Proteomics identification {ECO:0007829|MaxQB:A0A087WS02,
KW ECO:0007829|ProteomicsDB:A0A087WS02};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Sensory transduction {ECO:0000256|ARBA:ARBA00022606};
KW Vision {ECO:0000256|ARBA:ARBA00023305}.
FT DOMAIN 1..185
FT /note="Phosducin thioredoxin-like"
FT /evidence="ECO:0000259|Pfam:PF02114"
FT REGION 1..68
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..45
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 53..68
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 185
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000140843.2"
SQ SEQUENCE 185 AA; 21207 MW; 374B5EB5C7F2314C CRC64;
MEEAASQSLE EDFEGQATHT GPKGVINDWR KFKLESEDGD SIPPSKKEIL RQMSSPQSRD
DSKERMSRKM SIQEYELIHQ DKEDESCLRK YRRQCMQDMH QKLSFGPRYG FVYELETGEQ
FLETIEKEQK VTTIVVNIYE DGVRGCDALN SSLACLAVEY PMVKFCKIKA SNTGAGDRFS
TDVLP
//
