ID A0A087WVY8_HUMAN Unreviewed; 141 AA.
AC A0A087WVY8;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=ADAMTS like 5 {ECO:0000313|Ensembl:ENSP00000479786.1};
DE Flags: Fragment;
GN Name=ADAMTSL5 {ECO:0000313|Ensembl:ENSP00000479786.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000479786.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000479786.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057824; DOI=10.1038/nature02399;
RA Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E.,
RA Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A.,
RA Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S.,
RA Carrano A.V., Caoile C., Chan Y.M., Christensen M., Cleland C.A.,
RA Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J.,
RA Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M.,
RA Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W.,
RA Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V.,
RA Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D.,
RA McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I.,
RA Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L.,
RA Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A.,
RA She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M.,
RA Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J.,
RA Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA Rubin E.M., Lucas S.M.;
RT "The DNA sequence and biology of human chromosome 19.";
RL Nature 428:529-535(2004).
RN [2] {ECO:0000313|Ensembl:ENSP00000479786.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC027307; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A087WVY8; -.
DR SMR; A0A087WVY8; -.
DR MassIVE; A0A087WVY8; -.
DR PeptideAtlas; A0A087WVY8; -.
DR Antibodypedia; 52211; 30 antibodies from 14 providers.
DR Ensembl; ENST00000590562.5; ENSP00000479786.1; ENSG00000185761.11.
DR UCSC; uc060rdc.1; human.
DR HGNC; HGNC:27912; ADAMTSL5.
DR VEuPathDB; HostDB:ENSG00000185761; -.
DR GeneTree; ENSGT00940000160456; -.
DR HOGENOM; CLU_1942872_0_0_1; -.
DR Proteomes; UP000005640; Chromosome 19.
DR Bgee; ENSG00000185761; Expressed in apex of heart and 92 other cell types or tissues.
DR ExpressionAtlas; A0A087WVY8; baseline and differential.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 1.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR PANTHER; PTHR13723; ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE; 1.
DR PANTHER; PTHR13723:SF173; ADAMTS-LIKE PROTEIN 5; 1.
DR Pfam; PF00090; TSP_1; 1.
DR SMART; SM00209; TSP1; 1.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 1.
DR PROSITE; PS50092; TSP1; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A087WVY8,
KW ECO:0007829|ProteomicsDB:A0A087WVY8};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..42
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 43..141
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001831973"
FT NON_TER 141
FT /evidence="ECO:0000313|Ensembl:ENSP00000479786.1"
SQ SEQUENCE 141 AA; 15792 MW; 64F063EC29DACEF3 CRC64;
MGKLRPGRVE WLASGHTERP HLFQNLLLFL WALLNCGLGV SAQGPGEWTP WVSWTRCSSS
CGRGVSVRSR RCLRLPGEEP CWGDSHEYRL CQLPDCPPGA VPFRDLQCAL YNGRPVLGTQ
KTYQWVPFHG APNQCDLNCL A
//
