ID A0A087WYK3_HUMAN Unreviewed; 84 AA.
AC A0A087WYK3;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Transcriptional adapter 2-alpha {ECO:0000313|Ensembl:ENSP00000487758.1};
DE SubName: Full=Transcriptional adaptor 2A {ECO:0000313|Ensembl:ENSP00000481890.1};
DE Flags: Fragment;
GN Name=TADA2A {ECO:0000313|Ensembl:ENSP00000481890.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000481890.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000481890.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16625196; DOI=10.1038/nature04689;
RA Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA Chang J.L., Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S.,
RA Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E.,
RA Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K.,
RA LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J.,
RA Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A.,
RA Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K.,
RA Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT "DNA sequence of human chromosome 17 and analysis of rearrangement in the
RT human lineage.";
RL Nature 440:1045-1049(2006).
RN [2] {ECO:0007829|PubMed:28112733}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=28112733;
RA Hendriks I.A., Lyon D., Young C., Jensen L.J., Vertegaal A.C.,
RA Nielsen M.L.;
RT "Site-specific mapping of the human SUMO proteome reveals co-modification
RT with phosphorylation.";
RL Nat. Struct. Mol. Biol. 24:325-336(2017).
RN [3] {ECO:0000313|Ensembl:ENSP00000481890.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC004099; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC068400; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC068447; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC243654; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Ensembl; ENST00000619777.4; ENSP00000481890.1; ENSG00000276234.5.
DR Ensembl; ENST00000632804.1; ENSP00000487758.1; ENSG00000277104.4.
DR UCSC; uc060eki.1; human.
DR HGNC; HGNC:11531; TADA2A.
DR VEuPathDB; HostDB:ENSG00000276234; -.
DR GeneTree; ENSGT00940000156751; -.
DR HOGENOM; CLU_2548806_0_0_1; -.
DR ChiTaRS; TADA2A; human.
DR Proteomes; UP000005640; Chromosome 17.
DR Bgee; ENSG00000276234; Expressed in male germ line stem cell (sensu Vertebrata) in testis and 103 other cell types or tissues.
DR CDD; cd00167; SANT; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR017884; SANT_dom.
DR PANTHER; PTHR12374:SF20; TRANSCRIPTIONAL ADAPTER 2-ALPHA; 1.
DR PANTHER; PTHR12374; TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR SMART; SM00717; SANT; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51294; HTH_MYB; 1.
DR PROSITE; PS50090; MYB_LIKE; 1.
DR PROSITE; PS51293; SANT; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A087WYK3,
KW ECO:0007829|ProteomicsDB:A0A087WYK3};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT DOMAIN 7..59
FT /note="SANT"
FT /evidence="ECO:0000259|PROSITE:PS51293"
FT DOMAIN 11..59
FT /note="HTH myb-type"
FT /evidence="ECO:0000259|PROSITE:PS51294"
FT DOMAIN 11..55
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSP00000481890.1"
SQ SEQUENCE 84 AA; 9534 MW; BE888F1BB33B21D1 CRC64;
XTSDFPVLDP SWTAQEEMAL LEAVMDCGFG NWQDVANQMC TKTKEECEKH YMKHFINNPL
FASTLLNLKQ AEEAKTADTA IPFH
//
