ID A0A087WZ41_HUMAN Unreviewed; 137 AA.
AC A0A087WZ41;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Mitochondrial translation release factor 1 {ECO:0000313|Ensembl:ENSP00000482339.1};
DE Flags: Fragment;
GN Name=MTRF1 {ECO:0000313|Ensembl:ENSP00000482339.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000482339.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000482339.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057823; DOI=10.1038/nature02379;
RA Dunham A., Matthews L.H., Burton J., Ashurst J.L., Howe K.L.,
RA Ashcroft K.J., Beare D.M., Burford D.C., Hunt S.E., Griffiths-Jones S.,
RA Jones M.C., Keenan S.J., Oliver K., Scott C.E., Ainscough R., Almeida J.P.,
RA Ambrose K.D., Andrews D.T., Ashwell R.I.S., Babbage A.K., Bagguley C.L.,
RA Bailey J., Bannerjee R., Barlow K.F., Bates K., Beasley H., Bird C.P.,
RA Bray-Allen S., Brown A.J., Brown J.Y., Burrill W., Carder C., Carter N.P.,
RA Chapman J.C., Clamp M.E., Clark S.Y., Clarke G., Clee C.M., Clegg S.C.,
RA Cobley V., Collins J.E., Corby N., Coville G.J., Deloukas P., Dhami P.,
RA Dunham I., Dunn M., Earthrowl M.E., Ellington A.G., Faulkner L.,
RA Frankish A.G., Frankland J., French L., Garner P., Garnett J.,
RA Gilbert J.G.R., Gilson C.J., Ghori J., Grafham D.V., Gribble S.M.,
RA Griffiths C., Hall R.E., Hammond S., Harley J.L., Hart E.A., Heath P.D.,
RA Howden P.J., Huckle E.J., Hunt P.J., Hunt A.R., Johnson C., Johnson D.,
RA Kay M., Kimberley A.M., King A., Laird G.K., Langford C.J., Lawlor S.,
RA Leongamornlert D.A., Lloyd D.M., Lloyd C., Loveland J.E., Lovell J.,
RA Martin S., Mashreghi-Mohammadi M., McLaren S.J., McMurray A., Milne S.,
RA Moore M.J.F., Nickerson T., Palmer S.A., Pearce A.V., Peck A.I., Pelan S.,
RA Phillimore B., Porter K.M., Rice C.M., Searle S., Sehra H.K., Shownkeen R.,
RA Skuce C.D., Smith M., Steward C.A., Sycamore N., Tester J., Thomas D.W.,
RA Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P.,
RA Whitehead S.L., Willey D.L., Wilming L., Wray P.W., Wright M.W., Young L.,
RA Coulson A., Durbin R., Hubbard T., Sulston J.E., Beck S., Bentley D.R.,
RA Rogers J., Ross M.T.;
RT "The DNA sequence and analysis of human chromosome 13.";
RL Nature 428:522-528(2004).
RN [2] {ECO:0000313|Ensembl:ENSP00000482339.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AL354696; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A087WZ41; -.
DR SMR; A0A087WZ41; -.
DR MassIVE; A0A087WZ41; -.
DR PeptideAtlas; A0A087WZ41; -.
DR Antibodypedia; 23394; 181 antibodies from 22 providers.
DR Ensembl; ENST00000480434.5; ENSP00000482339.1; ENSG00000120662.16.
DR UCSC; uc058wpq.1; human.
DR HGNC; HGNC:7469; MTRF1.
DR VEuPathDB; HostDB:ENSG00000120662; -.
DR GeneTree; ENSGT00940000156877; -.
DR HOGENOM; CLU_1880150_0_0_1; -.
DR ChiTaRS; MTRF1; human.
DR Proteomes; UP000005640; Chromosome 13.
DR Bgee; ENSG00000120662; Expressed in body of pancreas and 188 other cell types or tissues.
DR ExpressionAtlas; A0A087WZ41; baseline and differential.
DR GO; GO:0006415; P:translational termination; IEA:InterPro.
DR Gene3D; 3.30.70.1660; -; 1.
DR Gene3D; 6.10.140.1950; -; 1.
DR InterPro; IPR005139; PCRF.
DR InterPro; IPR045853; Pep_chain_release_fac_I_sf.
DR PANTHER; PTHR43804; LD18447P; 1.
DR PANTHER; PTHR43804:SF1; PEPTIDE CHAIN RELEASE FACTOR 1, MITOCHONDRIAL; 1.
DR Pfam; PF03462; PCRF; 1.
DR SMART; SM00937; PCRF; 1.
DR SUPFAM; SSF75620; Release factor; 1.
PE 1: Evidence at protein level;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Proteomics identification {ECO:0007829|EPD:A0A087WZ41,
KW ECO:0007829|MaxQB:A0A087WZ41};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT DOMAIN 31..135
FT /note="Peptide chain release factor"
FT /evidence="ECO:0000259|SMART:SM00937"
FT COILED 9..43
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSP00000482339.1"
SQ SEQUENCE 137 AA; 16383 MW; CF6689497E422526 CRC64;
RRHAELAPLA AIYQEIQETE QAIEELESMC KSLNKQDEKQ LQELALEERQ TIDQKINMLY
NELFQSLVPK EKYDKNDVIL EVTAGRTTGG DICQQFTREI FDMYQNYSCY KHWQFELLNY
TPADYGRHIE EFACRRY
//
