ID A0A087X2W3_POEFO Unreviewed; 2220 AA.
AC A0A087X2W3;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Capicua transcriptional repressor a {ECO:0000313|Ensembl:ENSPFOP00000000116.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000000116.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000000116.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AYCK01008093; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Ensembl; ENSPFOT00000000116.2; ENSPFOP00000000116.2; ENSPFOG00000000116.2.
DR GeneTree; ENSGT00940000159960; -.
DR OMA; EHCAGNH; -.
DR UniPathway; UPA00115; UER00414.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004801; F:transaldolase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-UniPathway.
DR CDD; cd21990; HMG-box_CIC-like; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR InterPro; IPR032147; DUF4819.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR InterPro; IPR018225; Transaldolase_AS.
DR PANTHER; PTHR13059; HMG-BOX TRANSCRIPTION FACTOR BBX; 1.
DR PANTHER; PTHR13059:SF14; PROTEIN CAPICUA HOMOLOG ISOFORM X1; 1.
DR Pfam; PF16090; DUF4819; 1.
DR Pfam; PF00505; HMG_box; 1.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; HMG-box; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
DR PROSITE; PS01054; TRANSALDOLASE_1; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00267};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00267}; Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 955..1023
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 955..1023
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 1..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 252..276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 313..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 399..471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 507..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 539..605
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 622..683
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 864..954
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1153..1172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1180..1231
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1301..1352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1791..1916
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1938..2085
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2175..2220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 259..276
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..359
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 399..419
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 422..440
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 539..559
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 572..588
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 622..655
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 656..673
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 875..889
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 931..954
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1198..1231
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1317..1337
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1791..1812
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1828..1847
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1859..1907
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1948..1974
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1991..2018
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2046..2072
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2175..2191
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2197..2220
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2220 AA; 239131 MW; E67A1FFAB131A38C CRC64;
PASSRKTATF KARVPKKKYT SEHCSTATAS NHSDPPSSTP PPPSGGVLSR GPLPRCSSTD
TASEHSADLE VVGDMPAISH SMSHSAPSLP DTLSDTLAKG LKNQRVLARQ LKFVFRAGVV
RKVSGEFGCL EVQLNGEKTM CSYPYRHDSP PGVVEIILDA PPPGVHTIPI GTRVCVPFGD
EDSNEGQLQW YREGMVTEVD THPAVANRYR VLLSEGRPNS LDVEDSRGAT HAVWVSRQTL
RLLVPPWDLD LPSCGGHGGE EGVREKDKKH EEREDIDVEQ EVCTISQGMN IGMGLDSTNA
AAGAVITAPQ LPPLPPISSS ASSRAEKASG GGSSGGGGGP VSGSNSSSAN RSRTPLTAAQ
QKYKKGDVVC TPTGIRKKFN GKQWRRLCSR EGCSKESQRR GYCSRHLSMR TKEMEASGGG
RERSGASSTG TLTPSDLRLG SGRASSEFDW DETSMESSEA SSRGGDSRPR LVLPSLLPQD
LSRFDFDECE AATMLVSLGG SRSVTPSFSP ISNQSPFSPT PSPSPSPLFC FRPATFSPIT
APPSLNPRRP RQLSGTKMGT PGSERERHLS AIVPSIQTNL TFTVPMSPNK RRPETHPPPP
LHLVQDYQRG SLAGDPAAFR VLSPHSQSTT PSSLPFSRPR SATSRPSSSA ASTPPPMLVS
PTPPSPLPQE PSPRRIVPLR DSPVIVRNPD VPLAKFSDGP LVKRERNQLR EKNQPQHSTP
PGLQAPVPIN GATTNPAVLL RNPASTLVLV TSSSQPVACH PTPTALLPLI LPAESPHPAP
RKQIIMGRPG TAVWTNVEPR SVPVFPWHSL VPFLDSSQPG AAGQPADGQQ LVNQSKGSNM
TQLLFLDRGT TGSLDEPRCG VALVSEERAG PPEPDRGSPS RPPPTNDNPP ADRGGADSET
ESDTDDPFSP GVGNDPSPSA GPMKRRTQSL SALPKDGDRK AEKPLKSTQR EKDYIRRPMN
AFMIFSKRHR ALVHQRHPNQ DNRTVSKILG EWWYALGPNE KQKYHDLAFQ VKEAHFKAHP
DWKWCNKDRR KSLSEGRGTP KELRERSMSE SIVLLILSLM RLSSLSPRCA LGVPGAGGKR
WRSGLAGGIG AHPRPRAFSQ SAVHTLEQRE RQRELEKLLQ KRCEYETPVL AFLSGLYFHF
WVDEDGTGLF RSRPPPQSLY HSGANEDVTS DEERMVICEE EGDDDVMVPP SEDSCPDGSI
DLKCKERVTD SDEDEPDGQE PSRKQGKHKN APKIISKPDF CRWILNPKTD HETHAARQKP
FFLFVYISQR RKLRSVSSEF LILGAAPPQA SRGTAAVFLQ PESRSSPAVS DSSAKGEAEG
PGEDRKRGVE PAEQGEGGTR KNELSGGGSG VSVGPLQQGL PQVLGGVWVA PPAVRPATSA
PIAIASKPVD GGAALSSLPQ EKTNVLIGGA GAQLTAGGGY LSSSSSSSLI YTPRTPKSEV
THLFSVFLSS VQTQASVLPS KMLVPMATVR TGSTPPQPSI SLVAPPLPVQ NGPATGNKET
RNKQHGRTIQ LKNRQVCLWG KKCDCTNLKL PFRIVNAHFQ IIRIKILSAI HFETQHLSQC
DTLIFVVFTI FPSCFCLFFS SQIIQLTSMP VVQTNVHPSP GSPFPVSMAT VMAPGAVPPQ
PVLLTSPPTR SLKQHFAEHQ GKADKLQTKT FRIPEQLIKT NLNVTGKSCS SKGKHLTRLV
SLRITYVQSS PGVTTATPQQ GTQPPGPAYL SSHLATLGFT AIAPAGQTLV QPVLAQAPPL
AAQSQTPPGQ TAAGRQVLTA IYPAQTVALA TGVVPLAAAV PPAIASPAQD AINPASPSTK
AMQGSATAAT FQPGTGMKVE VKQESQLDSE TEGSSGCNPS CSMGSYENGG ATDFPVKKED
ISLSIKEENM RDETEMERQS EADEERDGVM KEAKETDRGD RNATNNSKEK TQTDGAKMIV
QEFHQLFSNM MTLSHVSETK AEPRFPHQAG PRSPPPPPPP PSGLDPPPPP PAEKETASSS
SSSKRIKFRP PPLKKTPDSH DKVLSETSFE ERFAELPEFN PEEVLPSPTL QSLATSPRAI
LGSYRKKRRN STDLDGAAED PSSPRRKSRR LSSCSSEPST PKSAAKCEGD IFTFDRPAGL
EGDVPLGDPD RVPYSSLRRT LDQRRALVMQ LFQEHGFFPS AQATASFQAR YPDTFPTKLC
LQLKIREVRQ KIMQTATPGT LEPSEAGPTL SHGQSAREDG GAEHQGDKGQ NLEEPKNEGS
//
