ID A0A087X6I0_POEFO Unreviewed; 424 AA.
AC A0A087X6I0;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 24-JAN-2024, entry version 46.
DE RecName: Full=Flotillin {ECO:0000256|RuleBase:RU366054};
GN Name=FLOT1 {ECO:0000313|Ensembl:ENSPFOP00000001383.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000001383.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000001383.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBUNIT: Heterooligomeric complex. {ECO:0000256|RuleBase:RU366054}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU366054}.
CC Endosome {ECO:0000256|RuleBase:RU366054}.
CC -!- SIMILARITY: Belongs to the band 7/mec-2 family. Flotillin subfamily.
CC {ECO:0000256|ARBA:ARBA00007161, ECO:0000256|RuleBase:RU366054}.
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DR EMBL; AYCK01010094; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007564344.1; XM_007564282.2.
DR AlphaFoldDB; A0A087X6I0; -.
DR STRING; 48698.ENSPFOP00000001383; -.
DR Ensembl; ENSPFOT00000001386.2; ENSPFOP00000001383.2; ENSPFOG00000001372.2.
DR GeneID; 103146382; -.
DR KEGG; pfor:103146382; -.
DR CTD; 561345; -.
DR eggNOG; KOG2668; Eukaryota.
DR GeneTree; ENSGT00560000077232; -.
DR OMA; ERQYDSE; -.
DR OrthoDB; 5486670at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd03399; SPFH_flotillin; 1.
DR Gene3D; 3.30.479.30; Band 7 domain; 1.
DR InterPro; IPR001107; Band_7.
DR InterPro; IPR036013; Band_7/SPFH_dom_sf.
DR InterPro; IPR031905; Flotillin_C.
DR InterPro; IPR027705; Flotillin_fam.
DR PANTHER; PTHR13806:SF33; FLOTILLIN; 1.
DR PANTHER; PTHR13806; FLOTILLIN-RELATED; 1.
DR Pfam; PF01145; Band_7; 1.
DR Pfam; PF15975; Flot; 1.
DR SMART; SM00244; PHB; 1.
DR SUPFAM; SSF117892; Band 7/SPFH domain; 1.
PE 3: Inferred from homology;
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU366054};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760}.
FT DOMAIN 84..266
FT /note="Band 7"
FT /evidence="ECO:0000259|SMART:SM00244"
SQ SEQUENCE 424 AA; 47485 MW; C64E8572214B688D CRC64;
MFYTCGPNEA MVVSGFCRSP PVMIAGGRVF VFPCIQQIQR ISLNTLTLNV KSDKVYTRHG
VPISVTGIAQ MKIQGQNKQM LAAACQMFMG KSEAEIAHIA LETLEGHQRA IIAHLTVEEI
YKDRKKFSEQ VFKVASSDLV NMGISVVSYT LKDVHDDQDY LHSLGKARTA QVQKDARIGE
ALNKRDAVIR EAHAMQEKIS AQYRNEIDMA KAQRDYELKK AAYDMEVNTK KAESEMAFQL
QVAKTKQRIE EEKMQVQVVE RAQQIMLQEQ EITRREKELE AKVKKPAEAE RYRLEKLAEA
QRMKMIMEAE AEAESIRVKG EAEAFAVEAK GRAEAEQMAK KAEAFREYKD GAMVDMLLEK
LPLMAEEISR PLCEANKVTM VSSGGGEVGA AKLSGEVLEI MTRLPEAVEK LTGVNISQVT
SRTG
//
