ID A0A087X6Q2_POEFO Unreviewed; 972 AA.
AC A0A087X6Q2;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Trafficking protein, kinesin binding 2 {ECO:0000313|Ensembl:ENSPFOP00000001455.2};
GN Name=TRAK2 {ECO:0000313|Ensembl:ENSPFOP00000001455.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000001455.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000001455.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
CC -!- SIMILARITY: Belongs to the milton family.
CC {ECO:0000256|ARBA:ARBA00007007}.
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DR EMBL; AYCK01018607; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A087X6Q2; -.
DR STRING; 48698.ENSPFOP00000001455; -.
DR Ensembl; ENSPFOT00000001458.2; ENSPFOP00000001455.2; ENSPFOG00000001467.2.
DR eggNOG; KOG4360; Eukaryota.
DR GeneTree; ENSGT00940000158202; -.
DR OMA; LDGSHKF; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR InterPro; IPR006933; HAP1_N.
DR InterPro; IPR022154; TRAK1/2_C.
DR PANTHER; PTHR15751; TRAFFICKING KINESIN-BINDING PROTEIN; 1.
DR PANTHER; PTHR15751:SF13; TRAFFICKING KINESIN-BINDING PROTEIN 2; 1.
DR Pfam; PF04849; HAP1_N; 1.
DR Pfam; PF12448; Milton; 1.
DR SMART; SM01424; HAP1_N; 1.
DR SMART; SM01423; Milton; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760}.
FT DOMAIN 38..339
FT /note="HAP1 N-terminal"
FT /evidence="ECO:0000259|SMART:SM01424"
FT DOMAIN 399..544
FT /note="Trafficking kinesin-binding protein C-terminal"
FT /evidence="ECO:0000259|SMART:SM01423"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 485..507
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 586..659
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 685..714
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 735..760
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 795..843
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 926..972
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 127..161
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 189..332
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..18
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 597..611
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 814..837
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 972 AA; 106619 MW; 84F903D026A8BD8D CRC64;
MFEAKPRTVE KKESSTETDE GLGSSGRHYT SSSLGSCSAG SGSLYLSDSQ DWVVSPSCSP
DEPPTQISSI SPMLAEETLR YMILGANRVE QMTKTYNDIE VVTHLLAERD RDLELAARIG
QSLLQRNHLL QERNDAVEEQ LAQAVDQVHQ LQHELNKKDE LLRIVASASE EGEQDPTVST
PQQQPQAAAV AALGQLEQLQ NKLEELEEEN LALRSEACQL KRDTMTYEEK EQQLVSDCVK
ELRESNSQMV SLTDELSQKN EELLRHQEEI AQLLSQIVEL QHRVKELALE KEELRIHLQA
SKDAQRQLTA ELNELAERNA ECVEMLHESQ DEIRDLRSRS SPSSGMRRHL SYGLFPMESL
AAEIEGSMRR ELSIDEETAF QDQRISLKRV FQTVRSVNAS ASRAALATPP IPGSGQSSLV
MTAQPFQSAQ GQDIMTYPKS GCRDEVQMGK PGLPGGNDLT KALHRLSLRR QNFLSERQFF
QAEREKKLQN QTGAEADGEG SDCSSPMGSV LSSFSNLSDL TVGSTVFKTF LPEKLQIVKP
IEGSLTLHHW QQLAQPHLAT ILDPHPGVVT KGFRPLAQDA MFQLSDMEED EEAEEHRETA
ALEKGTAEKG KEELDEEEEE CGITFNVRCS STPEDRNHPV APLPSIRSTS PGAPSTSSFV
PSDLYLTPNH VTEKSNQLAL PIPGASTTTV QSQSRASTST TSSCVQNPGK SQSSTFSTYT
FTTCRILHPT DITQVTPSSQ SSISANTPSS MRTGPSTPVT PCRLSLGDSF PPRRPPAPPC
GLAKLVLERG ISAQVSTDVP SPLPRSAPRQ PLLRLMPSTP PNSPSHSPTP SPLPMEPRQH
PSDNFLASRP AELFLQDVYG LNPGRDKANP PSVSLVERLR RLGFTKVLHN SESDTPVPHQ
ESATFVSAGG GSLMDGLRRN QSLPAMIGAR AGSKSTGHPP HPTSLAIPPP PWGNLKERRR
HLASISHPPR SS
//
