ID A0A087X973_POEFO Unreviewed; 802 AA.
AC A0A087X973;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 24-JAN-2024, entry version 53.
DE SubName: Full=CCR4-NOT transcription complex subunit 4 {ECO:0000313|Ensembl:ENSPFOP00000002326.2};
GN Name=CNOT4 {ECO:0000313|Ensembl:ENSPFOP00000002326.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000002326.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000002326.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AYCK01002236; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01002237; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01002238; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007546705.1; XM_007546643.2.
DR RefSeq; XP_007546706.1; XM_007546644.2.
DR AlphaFoldDB; A0A087X973; -.
DR STRING; 48698.ENSPFOP00000002326; -.
DR Ensembl; ENSPFOT00000002330.2; ENSPFOP00000002326.2; ENSPFOG00000002228.2.
DR GeneID; 103134414; -.
DR KEGG; pfor:103134414; -.
DR CTD; 569055; -.
DR eggNOG; KOG2068; Eukaryota.
DR GeneTree; ENSGT00390000000068; -.
DR OMA; ESPPHWL; -.
DR OrthoDB; 1748at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0030014; C:CCR4-NOT complex; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR CDD; cd16618; mRING-HC-C4C4_CNOT4; 1.
DR CDD; cd12438; RRM_CNOT4; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR034261; CNOT4_RRM.
DR InterPro; IPR039780; Mot2.
DR InterPro; IPR039515; NOT4_mRING-HC-C4C4.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR003954; RRM_dom_euk.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12603; CCR4-NOT TRANSCRIPTION COMPLEX RELATED; 1.
DR PANTHER; PTHR12603:SF0; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF14570; zf-RING_4; 1.
DR SMART; SM00361; RRM_1; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
DR PROSITE; PS50103; ZF_C3H1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00723}; Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00723}.
FT DOMAIN 14..57
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 109..193
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 190..217
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT ZN_FING 190..217
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 255..350
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 404..437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 492..532
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 547..578
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 648..667
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 754..802
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 68..98
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 260..290
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 326..346
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 423..437
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 547..567
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 648..664
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 757..771
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 802 AA; 86776 MW; 10B03C8B7EBCF257 CRC64;
MSHSPEMKDD PMECPLCMEP LEIDDVNFFP CTCGYQICRF CWHRIRTDEN GLCPACRKPY
PEDPAVYKPL SQEEIQRIKN EKKQKQNEKK QKVTENRKHL ASVRVVQRNL VFVVGLSQRL
ADPEVLKRPE YFGRFGKIHK VVINNSTSYA GSQGPSASAY VTYIRSEDAL RAIQCVNNVV
VDGRTLKASL GTTKYCSYFL KSMQCPKPDC MYLHELGDEA ASFTKEEMQA GKHQEYEQKL
LQDLYKINPG FLQPPACGTE KSKSKPNSTQ RTNSSNGKDS WPTLSGHNKL ANGLSEDRKS
PPLLDYLDQE ASNSDGLESE LGPGQRPTLS PFSSNCDSNS PNDKPPESIG MVNGEALQQM
PTSDSPSPPP GLTKPILVVP ISMSDLSARS PFEGAAAESQ SLFSDNSNFR HPNPLPAGLP
PFPSSSRGSS DWPMTPEPQI LFTSDTIPVS SSTDWQAAFG FGSSSKQQDD DLGFDPFDVT
RKALADLIEK ELSVQDQSPS SPGPLAPGSG HTPGLPPSNL STSHHFPGGL PRVHPLHHRA
FYSSFSFPGG HNSQAGQQQQ QQQLPATRHP WMGIPTRNNL AHLNHSASAA SHSNILDLNL
PPQHNTGLGG IPISENSSSI DGLNVKEWQD GLRALLPNIN INFGGLPNSS SSSSSSSSNS
VNHIGGPAGP AGISHSLSWD STASWMDPAI ITGIPASAGS SLDCLQDDNP PHWLKSLQAL
TEMDGPASSA VPAPPQPLHS GLLDGHLPLH HRAPSGWAPY LPPPTANPTG QFHSPPPGFQ
TAFRPPGQPA TELLQSAAVD RH
//
