ID A0A087X9D6_POEFO Unreviewed; 254 AA.
AC A0A087X9D6;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Helt bHLH transcription factor {ECO:0000313|Ensembl:ENSPFOP00000002389.1};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000002389.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000002389.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AYCK01004552; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A087X9D6; -.
DR STRING; 48698.ENSPFOP00000002389; -.
DR Ensembl; ENSPFOT00000002393.1; ENSPFOP00000002389.1; ENSPFOG00000002530.1.
DR eggNOG; KOG4304; Eukaryota.
DR GeneTree; ENSGT00940000160388; -.
DR OMA; GHTHANA; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd11408; bHLH-O_HELT; 1.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR003650; Orange_dom.
DR PANTHER; PTHR10985; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED; 1.
DR PANTHER; PTHR10985:SF8; HAIRY AND ENHANCER OF SPLIT-RELATED PROTEIN HELT; 1.
DR Pfam; PF07527; Hairy_orange; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR SUPFAM; SSF158457; Orange domain-like; 1.
DR PROSITE; PS50888; BHLH; 1.
DR PROSITE; PS51054; ORANGE; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT DOMAIN 29..84
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT DOMAIN 106..141
FT /note="Orange"
FT /evidence="ECO:0000259|PROSITE:PS51054"
FT REGION 164..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 172..192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 254 AA; 28871 MW; C627DBEA4833820A CRC64;
LGFVNRRSCE KRELEQYSSM ASKMKDRKRT PISHKVIEKR RRDRINRCLN ELGKTVPMAL
AKQNSGKLEK AEILEMTVQY LRALHSADFP RGREKGELLA EFANYFHYGY HECMKNLVHY
LTTEDRAETK DIKYARILAF LQSKSRAVTE PVFGSVGSMS DPPDYLGHLH SSPEHQSHSP
SDSVYQQSPT GHFSWHGSGR SQGISYPAVP LSAHTQQHGG YLSPVQGLDH HYFNFIGHTH
ANTFSLHSAQ HAIL
//
