ID A0A087XAB7_POEFO Unreviewed; 948 AA.
AC A0A087XAB7;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A {ECO:0000313|Ensembl:ENSPFOP00000002720.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000002720.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000002720.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR EMBL; AYCK01006961; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01006962; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01006963; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A087XAB7; -.
DR Ensembl; ENSPFOT00000002724.2; ENSPFOP00000002720.2; ENSPFOG00000002593.2.
DR GeneTree; ENSGT00940000156565; -.
DR OMA; CRTYKVR; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR GO; GO:0048468; P:cell development; IEA:UniProt.
DR GO; GO:0022008; P:neurogenesis; IEA:UniProt.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR PANTHER; PTHR11036:SF12; SEMAPHORIN-6A; 1.
DR Pfam; PF01437; PSI; 1.
DR Pfam; PF01403; Sema; 1.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 584..610
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..451
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT REGION 286..312
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 692..714
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 849..948
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 849..875
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 891..914
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 948 AA; 105475 MW; EF170FF69222AC03 CRC64;
FLKFKHSLYK VPRDHIYTVD TETANGDEIF FSKKMTWKSR QADVDTCRMK GKHKDECHNF
IKVLLQQNGD TLFVCGTNAF NPSCRTYKMD SLEALGEEIS GMARCPYDAK HANVALFADG
KLYSATVTDF LAIDAVIYRS LGDSPTLRTV KHDSKWLKEP YFVQAVNYGD FIYFFFREIA
MEYNTMGKVV FPRVARVCKN DRGGSPRVLE KQWTSFLKSR LNCSIPGDSH FYFNILQAVT
DVIHINGRDV VMATFSTPYN SIPGSAVCAY DMAEVARAFT GRFKEQKSPD STWTPFPEER
VPKPRPGSCA GTPSMERYKV SNEFPDDTLN FIKMHPLMDE AVPSIAHRPW FLKTMVRYRL
TRIVVDNEAG PHRNHTVVFL GSEKGIILKF LAKMNKGFLN DSLFLEELNV YNPDKCSIDG
VEDKRIIGMQ IDSKSNALWV AFTSCVVKVP LSRCERHGRC KKSCIASRDP YCGWVSEGAC
RQVTTNTKSA FEQDVEHGNT DGLGDCQNTF VALNGKCSSS TSRQSPPLLI SEGVQSLWAP
CSLDEPNTHV IDKGEDPYVA VPSQTQPEAT GVIRESYQKG RDQLVPVTLL AIAVILAFAM
GAIFSGLIVY CVCDHRRRDL DLTGRKEKDS LHLHSRRGSM NSVTKLTGLF ETQAKDGRPE
AILTPLMHNG RLTPNAKMLI KADQHHLDLA ALPTPESTPM QPRRKPSRGS REWERNQNLI
NACTKDMPPI GSPVISTDLP LRASPGHIPS VVVLPLPQHQ HQLPPHLQQS YQHEYVEQPH
HSDLGMAHGV MEDQGATLEY KPGKSHMMDA DGMLPPRVPQ REASLTVPPA VPQMGKRLEV
HSSVYGLRKG SASSASGSSA LKKHNTNSSN SSHLSRHHSF RVETPPPAPQ RVDSIQMTTQ
GISLSRQPGM ITYGSLPRTG SKHLKPDVPP KPSVVSLSTK AKSSDSGT
//
