ID A0A087XAI4_POEFO Unreviewed; 475 AA.
AC A0A087XAI4;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 24-JAN-2024, entry version 49.
DE SubName: Full=Friend leukemia integration 1 transcription factor-like {ECO:0000313|Ensembl:ENSPFOP00000002787.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000002787.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000002787.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
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DR EMBL; AYCK01009447; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01009448; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007562808.1; XM_007562746.2.
DR AlphaFoldDB; A0A087XAI4; -.
DR STRING; 48698.ENSPFOP00000002787; -.
DR Ensembl; ENSPFOT00000002791.2; ENSPFOP00000002787.2; ENSPFOG00000002827.2.
DR GeneID; 103145351; -.
DR KEGG; pfor:103145351; -.
DR CTD; 2313; -.
DR eggNOG; KOG3806; Eukaryota.
DR GeneTree; ENSGT00940000158261; -.
DR OrthoDB; 2882052at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd08541; SAM_PNT-FLI-1; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR003118; Pointed_dom.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR035573; SAM_PNT-FLI-1.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849; ETS; 1.
DR PANTHER; PTHR11849:SF161; FRIEND LEUKEMIA INTEGRATION 1 TRANSCRIPTION FACTOR; 1.
DR Pfam; PF00178; Ets; 1.
DR Pfam; PF02198; SAM_PNT; 1.
DR PRINTS; PR00454; ETSDOMAIN.
DR SMART; SM00413; ETS; 1.
DR SMART; SM00251; SAM_PNT; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
DR PROSITE; PS51433; PNT; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|RuleBase:RU004019};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..475
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001832576"
FT DOMAIN 136..222
FT /note="PNT"
FT /evidence="ECO:0000259|PROSITE:PS51433"
FT DOMAIN 304..384
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
FT REGION 53..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 223..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..77
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 251..285
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 475 AA; 53586 MW; 444B8A37522CA49D CRC64;
MWAHWTLSTL GPVCLVDMFQ TVPDTSSYVK EALSVVSEDQ SLFEPPYAAA APLPKTDMTA
SGTQDYSQTH KINPLPPQQE WINQPVRVNV KREYEHMNGS SRESPVDCSV GKCNKLVGAN
DTSQMTYGSY MDEKNAPPPN MTTNERRVIV PADPSLWSQD HVRQWLEWAI KEYGLLEIDT
SMFQNTDGKE LCKMSKDDFL RLTTLYNAEV LLSHLNYLRE SSSSLSYNTP SHTDASPRLA
AKEDPSYDAV RRTGWSNNMH SGKGSPVVPQ NVTKSTEQAR PQPDPYQILG PTSSRLANPG
SGQIQLWQFL LELLSDSANA GCITWEGTNG EFKMTDPDEV ARRWGERKSK PNMNYDKLSR
ALRYYYDKNI MTKVHGKRYA YKFDFHGIAQ ALQPHPTESS MYKYPSDLAY VPSYHAHQQK
VNFVSPHPPS MPVTSSNFFG PTAQYWSSPT AGIYPNPNVP RHPNTHVPSH LGSYY
//
