ID   A0A087XC50_POEFO        Unreviewed;       787 AA.
AC   A0A087XC50;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   SubName: Full=Mtr4 exosome RNA helicase {ECO:0000313|Ensembl:ENSPFOP00000003353.1};
OS   Poecilia formosa (Amazon molly) (Limia formosa).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000003353.1, ECO:0000313|Proteomes:UP000028760};
RN   [1] {ECO:0000313|Proteomes:UP000028760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA   Schartl M., Warren W.;
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPFOP00000003353.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   EMBL; AYCK01007564; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A087XC50; -.
DR   STRING; 48698.ENSPFOP00000003353; -.
DR   Ensembl; ENSPFOT00000003359.1; ENSPFOP00000003353.1; ENSPFOG00000003141.1.
DR   eggNOG; KOG0948; Eukaryota.
DR   GeneTree; ENSGT00940000156183; -.
DR   OMA; IMLKNYN; -.
DR   Proteomes; UP000028760; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR   GO; GO:0006401; P:RNA catabolic process; IEA:InterPro.
DR   CDD; cd13154; KOW_Mtr4; 1.
DR   CDD; cd18795; SF2_C_Ski2; 1.
DR   Gene3D; 1.10.3380.30; -; 2.
DR   Gene3D; 2.40.30.300; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR048392; MTR4-like_stalk.
DR   InterPro; IPR025696; MTR4_beta-barrel.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016438; SKI2-like.
DR   InterPro; IPR012961; Ski2/MTR4_C.
DR   PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR   PANTHER; PTHR12131:SF7; EXOSOME RNA HELICASE MTR4; 1.
DR   Pfam; PF08148; DSHCT; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF21408; MTR4-like_stalk; 1.
DR   Pfam; PF13234; MTR4_beta-barrel; 1.
DR   PIRSF; PIRSF005198; Antiviral_helicase_SKI2; 1.
DR   SMART; SM01142; DSHCT; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028760}.
FT   DOMAIN          119..323
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          95..115
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   787 AA;  89083 MW;  310A3A5147068D8F CRC64;
     SERGVVWEET IILLPDNVHY VFLSATIPNA KQFAEWICHL HKQPCHVVYT DYRPTPLQHY
     IFPAGGDGLH LVVDENGDFR EDNFNTAMQV LRDLGESGGG SGGGKWDRNR KGGTKGPSSV
     FKIVKMIMER NFQPVIIFSF SKKDCEAYAL QVSKLDFNND DEKRLVEEVF NNAVDCLSDE
     DKKLPQVEHV LPLLKRGIGI HHGGLLPILK ETIEILFSEG LLKALFATET FAMGINMPAR
     TVLFTSARKF DGKNHRFITS GEYIQMSGRA GRRGMDDRGI VIFMVDEKMS PAVGKQLLKG
     SADPLNSAFH LTYNMVLNLL RVEEINPEYM LEKSFYQFQH YRALPGVVEK IKKLEDQYHT
     IEIPNEESVV TYFKIRQQLA KLGKEIQEFI HKPKYCLPFL QPGRLVKVKN EDTDFGWGVV
     VNFSKKTNTK ASGDSEPLYV VEVLLHCSKE SVKNSATEAA KPAAPGETGE MQVVPVMLHL
     LTSISSVRLY IPKDLRPFDN RQLMLKSIQE VQKRFPDGVP LLDPIDDMGI KDPGLKKVIQ
     KVEAFEHRMY THTLHSDPNL ESVYSLCERK AQIAAEVRTA KRELKKARTV LQMDELKCRK
     RVLRRLGFAS PSDVIEMKGR VACEISSADE LLLTEMVFNG LFNDLTVEQA TALLSCFVFQ
     ENANEMPKLT EQLAAPLRQM QECAKRIAKV SADAKLEVDE ETYLNQFKPH LMDVVFAWAN
     GATFAQICKM TDVFEGSIIR CMRRLEEVLR QMCSAAKAIG NTELENKFSE GITKIKRDIV
     FAASLYL
//