ID   A0A087XE92_POEFO        Unreviewed;       584 AA.
AC   A0A087XE92;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   RecName: Full=Nephronectin a {ECO:0008006|Google:ProtNLM};
OS   Poecilia formosa (Amazon molly) (Limia formosa).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000004095.1, ECO:0000313|Proteomes:UP000028760};
RN   [1] {ECO:0000313|Proteomes:UP000028760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA   Schartl M., Warren W.;
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPFOP00000004095.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the nephronectin family.
CC       {ECO:0000256|ARBA:ARBA00009738}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AYCK01012337; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AYCK01012338; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A087XE92; -.
DR   STRING; 48698.ENSPFOP00000004095; -.
DR   Ensembl; ENSPFOT00000004103.1; ENSPFOP00000004095.1; ENSPFOG00000003998.1.
DR   eggNOG; KOG1217; Eukaryota.
DR   GeneTree; ENSGT00930000150973; -.
DR   OMA; SPKCRCK; -.
DR   Proteomes; UP000028760; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR   CDD; cd00054; EGF_CA; 2.
DR   CDD; cd06263; MAM; 1.
DR   Gene3D; 2.60.120.200; -; 1.
DR   Gene3D; 2.10.25.10; Laminin; 4.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR   InterPro; IPR000742; EGF-like_dom.
DR   InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR   InterPro; IPR018097; EGF_Ca-bd_CS.
DR   InterPro; IPR000998; MAM_dom.
DR   PANTHER; PTHR24050:SF19; NEPHRONECTIN; 1.
DR   PANTHER; PTHR24050; PA14 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF07645; EGF_CA; 2.
DR   Pfam; PF00629; MAM; 1.
DR   SMART; SM00181; EGF; 4.
DR   SMART; SM00179; EGF_CA; 2.
DR   SMART; SM00137; MAM; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   SUPFAM; SSF57196; EGF/Laminin; 2.
DR   PROSITE; PS00010; ASX_HYDROXYL; 2.
DR   PROSITE; PS00022; EGF_1; 1.
DR   PROSITE; PS01186; EGF_2; 1.
DR   PROSITE; PS50026; EGF_3; 1.
DR   PROSITE; PS01187; EGF_CA; 1.
DR   PROSITE; PS50060; MAM_2; 1.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW   ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000028760}.
FT   DOMAIN          199..236
FT                   /note="EGF-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50026"
FT   DOMAIN          440..584
FT                   /note="MAM"
FT                   /evidence="ECO:0000259|PROSITE:PS50060"
FT   REGION          324..354
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        333..350
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   584 AA;  63903 MW;  7B1327A7FD207330 CRC64;
     FFIQFSLIIG KNVYFLGRTE RDGNWTDQAV LSDGLCHYGN GVECCWGWRR TGRGRCQPDC
     QQGCKHGDCV GPDSCKCHPG YTGKACNQDT RFNPPVINRA RGQRLIQQAD MRSERCVSDL
     NECGVKPRPC KHRCMNTAGS FKCFCLDGFA LQPDGSCRNV RTCFHANCQY GCEVMKGEVR
     CTCPSPGLRL GPDRRSCVDI DECALGAACP RRRKCVNTFG SFFCKCHLGF KLTFIDGRYA
     CIVVNSVNKY KNKDTRPFCS LNPSSPKCRC KDGSCKGILR VTLEPHRPRT STTVSSTAYQ
     TTAALTTTVI ATTSMATSTV AMTTRSPITQ PATTVPTTPP TVPATAAPTT PTPLPATAAT
     TAAQPTVAIA TTTLPSSTGA VVTTTLNNRI NKDVTQRQRG DVHIPRQPGQ NHVWEFDIEL
     GNTAQDAQDD PGTASWVSAQ ICSFSRGVCS WISERDGDLS WESVDAPAGG RYLSVPELKE
     GQRSVRGARL AVQILPPWNR GDACFSFSHW LTGRQVGVLQ LFVRKKGRYG SALWSRTGGQ
     GWRQTQVTLE TQSVDKVSLK AERRPGRRGQ IAVDDVTLRR GACR
//