ID A0A087XEM7_POEFO Unreviewed; 659 AA.
AC A0A087XEM7;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=G protein signaling modulator 2 {ECO:0000313|Ensembl:ENSPFOP00000004230.1};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000004230.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000004230.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GPSM family.
CC {ECO:0000256|ARBA:ARBA00006600}.
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DR EMBL; AYCK01012168; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007567983.1; XM_007567921.2.
DR RefSeq; XP_016535073.1; XM_016679587.1.
DR AlphaFoldDB; A0A087XEM7; -.
DR STRING; 48698.ENSPFOP00000004230; -.
DR Ensembl; ENSPFOT00000004238.1; ENSPFOP00000004230.1; ENSPFOG00000004266.1.
DR GeneID; 103148926; -.
DR KEGG; pfor:103148926; -.
DR CTD; 29899; -.
DR eggNOG; KOG1130; Eukaryota.
DR GeneTree; ENSGT00940000154667; -.
DR OMA; PEDRSFH; -.
DR OrthoDB; 4190321at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0030695; F:GTPase regulator activity; IEA:InterPro.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR003109; GoLoco_motif.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45954:SF3; G-PROTEIN-SIGNALING MODULATOR 2; 1.
DR PANTHER; PTHR45954; LD33695P; 1.
DR Pfam; PF02188; GoLoco; 3.
DR Pfam; PF13374; TPR_10; 1.
DR Pfam; PF13424; TPR_12; 2.
DR Pfam; PF13176; TPR_7; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00390; GoLoco; 3.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50877; GOLOCO; 3.
DR PROSITE; PS50005; TPR; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 65..98
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 244..277
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 471..494
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 513..570
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 609..628
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 471..489
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 521..553
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 659 AA; 73080 MW; 8FA508105851E3E0 CRC64;
MDTGGSVVSM RTEEQPFHVR YRMEVSCLEL ALEGERLCKV GDYRAGVSFF EAAIQLGTAD
LQVLSAIYSQ LGNAYFHLHD YAKALEFHRH DLTLTRTIGD LLGEAKASGN LGNTLKVLGR
FDEAVVCCQR HLDIARDIND KIGQARALYN FGNVYHAKGK SICWSGAEPG DFPEEVMTAL
KKAAEFYEAN LAIVKELGDR AAQGRTYGNL GNTHYLLGNF GKAVASHEQR LLIAKEFGDR
SAERRAYCNL GNAFIFLGEF EVAAEHYKRS LQLARQLKDR AVEAQACYSL GNTYTLLQDY
ERAIDYHLKH LIIAQDLNDR IGEGRACWSL GNAHTALGNH DQAMHFAEKH LEICKETGDR
SGELTARMNV SDLQTVLGLS YSTNNSTLSE NKEIDYNLHG AKPRMSRRHS MENLELVKLT
PDKMNGQKWS SDILTKQSKP SLAKSSSKLF FVSRLRGKKY KIGGSTKVLQ DTSNTLDTSQ
TSTQGPQKRL SPEMLGDEGF FDLLSRFQSN RMDDQRCSVQ DRGSRLSLNS GPDSPPRTIR
KSVSESVNLA GSSGRRLEES AAAGGSLPGL RLNQSSNQAV LNHLMANADN AEPDEDFFDM
LVKCQGSRLD DQRCAPPPPP VRGPTVPDED FFSLIMRSQA KRMDEQRVTL PSAARSSSD
//
