ID A0A087XJ01_POEFO Unreviewed; 932 AA.
AC A0A087XJ01;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 24-JAN-2024, entry version 47.
DE SubName: Full=Probable ribonuclease ZC3H12C {ECO:0000313|Ensembl:ENSPFOP00000005754.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000005754.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000005754.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the ZC3H12 family.
CC {ECO:0000256|ARBA:ARBA00010922}.
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DR EMBL; AYCK01010676; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007565397.1; XM_007565335.2.
DR RefSeq; XP_016533630.1; XM_016678144.1.
DR AlphaFoldDB; A0A087XJ01; -.
DR STRING; 48698.ENSPFOP00000005754; -.
DR Ensembl; ENSPFOT00000005763.2; ENSPFOP00000005754.2; ENSPFOG00000005817.2.
DR GeneID; 103147134; -.
DR KEGG; pfor:103147134; -.
DR eggNOG; KOG3777; Eukaryota.
DR GeneTree; ENSGT00940000155107; -.
DR OMA; RSPDCRY; -.
DR OrthoDB; 180910at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd18729; PIN_Zc3h12-like; 1.
DR Gene3D; 3.40.50.11980; -; 1.
DR InterPro; IPR040546; Rege-1_UBA-like.
DR InterPro; IPR040757; Regnase_1/ZC3H12_C.
DR InterPro; IPR021869; RNase_Zc3h12_NYN.
DR InterPro; IPR000571; Znf_CCCH.
DR PANTHER; PTHR12876; N4BP1-RELATED; 1.
DR PANTHER; PTHR12876:SF36; RIBONUCLEASE ZC3H12C-RELATED; 1.
DR Pfam; PF18561; Regnase_1_C; 1.
DR Pfam; PF11977; RNase_Zc3h12a; 1.
DR Pfam; PF18039; UBA_6; 1.
DR PROSITE; PS50103; ZF_C3H1; 1.
PE 3: Inferred from homology;
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00723}; Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00723}.
FT DOMAIN 401..426
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT ZN_FING 401..426
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 31..143
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 187..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 538..560
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 582..610
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 697..756
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 795..880
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..59
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 81..96
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 106..139
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 700..717
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 836..875
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 932 AA; 101269 MW; 6037EB393D99D36E CRC64;
MGQKDHVEAG AVLDLAPDLE YLHVAGADRQ AGALDGPPAM EEQVESFSTT NTTVVGSPPK
ESGGSDGEYK SAPPATADSD GGEVSYTSSK NTHQPLCRTP CVDLGTEGPP EPPSDPSGGP
ERDPPEPPAD CPAPEPAPKP AGKEYQAKLE FALKLGYSED TVRQVLSKLG PDTLINDILG
ELVKLGTKPD SEQPAGILTS TSSSSSSSSC GCSDVLDGQR SDSPLPSESL CDQDNLRPIV
VDGSNVAMSH GNKEVFSCQG IQLAVDWFVE RGHQEVTVFV PAWRKEQSRP DAPITDQEIL
RRLEKEKILV FTPSRRVQGR RVVCYDDRFI VKLAYESDGI IVSNDNYRDL ANEKPEWKKF
IDERLLMYSF VNDKFMPPDD PLGRHGPSLD NFLRKRPIMP EQKKQPCPYG KKCTYGHKCK
YYHPERGAQP QRAVADELRA SAKSCVPYKN QGDAGLVKSH SVPAGTIEAK NGAPKRQSDP
SIRALSYSDA EEKLLVKSRL ESQKSNIGGS SSSSSCSSIS CGGGLAVSSA LAGPSPGFGL
LQDQQSRSGT HLPAPSHDLY PHCETPDLSY YSVTRAYSGL SLSSRRSPDC RYPNDQELRH
GSMGSAGSEC GSESSVSCGS SDSYSDRSCP GCPPDPLLEE SVHFPNPASR LYPHHIASNH
ELCSLHAADY PSIQHNHTSN PAVHSYHLNA ACGQSCVHEQ PPPEGPPKRP LYPLPPHLQH
QPLAARSSCP GDYHSLPQSN RQPPGSPIGR CLAPTRGESV SDSHLYEHLS ASHHHHRLKT
LPSWETYYRQ PSLPPSRYEP SAYQSLPDAH QSSWHPAPWP QEGYSSSHPG LHPSPTRYLG
HPPPPALSPH PPYPPHSSHL ALLSHPPPPY GPQHPESPVH GRYEDVREKV YVDLCNIFPS
ELVRRVMARS PHVTDPQQLA AAILAEKAQS GY
//
