ID A0A087XNA3_POEFO Unreviewed; 676 AA.
AC A0A087XNA3;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Neurofilament light polypeptide-like {ECO:0000313|Ensembl:ENSPFOP00000007256.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000007256.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000007256.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AYCK01009705; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007563381.1; XM_007563319.2.
DR AlphaFoldDB; A0A087XNA3; -.
DR STRING; 48698.ENSPFOP00000007256; -.
DR Ensembl; ENSPFOT00000007268.2; ENSPFOP00000007256.2; ENSPFOG00000007321.2.
DR GeneID; 103145748; -.
DR KEGG; pfor:103145748; -.
DR CTD; 793912; -.
DR eggNOG; ENOG502QSXY; Eukaryota.
DR GeneTree; ENSGT00940000156208; -.
DR OMA; SRFNVGM; -.
DR OrthoDB; 4640531at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR PANTHER; PTHR45652; GLIAL FIBRILLARY ACIDIC PROTEIN; 1.
DR PANTHER; PTHR45652:SF8; NEUROFILAMENT LIGHT POLYPEPTIDE; 1.
DR Pfam; PF00038; Filament; 1.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760}.
FT DOMAIN 88..399
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 452..676
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 92..224
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 318..377
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 462..536
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 537..562
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 574..676
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 676 AA; 75991 MW; 0C81E7711EE94E5B CRC64;
MSSIGYDPYY ASSLYKHLYV EPTSRVVVRG RTHAGYSSRA FPQSSSRLQY SSPSRVLFSS
SSPASSLERE LSQAAQISSD FRAVRTQERG QLQELNDRFA SFIERVRELE QQNRALEAEL
LLLRQRHAEP SRLRALYEQE ARTLRAAVDE ARAEQQTVLG QRERLEQTLN SLQGRYEEEM
LAREEAEGKL MEARREADEA ALGMAELEKG VETLLDELTF LKRIHEGEVA ELQTQVQLGV
QVAVESEAAA PDLSGALRDI RSQYERLAAR NMQAAEEWFR GKVGSLTETV AQHSSAVKSS
KDEAGEYRRQ LQARILEIDA CRGLNVSLEK QLHEMEEKQS AEIAAMHDTI GELENELRGT
KQEMARYLKE YQDLLNVKMA LDIEIAAYRK LLEGEESRFS VGVPGGVASL YSHSMVAPFF
ARPMLSSLSS GTSYLMTSRL LSSSTTEGII SASHAQQAEA SPPAEEEEEE EEAEEVKGEE
EEEQEEEEGG EEQKEEEEEE QEEKEEGGEQ EEEKGEEEAK EEDEEVKEEE GGDGGDVEQA
EGEKEEKGEG GEAEVKAEAQ EEETTEATED EDEKAKDEEK VEKGESKESE EKEVKEESKK
SEEKEEKGES KKSDEKEEKK ESKKSEEKAE KADAKKEDKP DVKEAAPKKD EAKKEKVEEK
AAKPEPAEEK STTGKK
//
