ID A0A087XP36_POEFO Unreviewed; 810 AA.
AC A0A087XP36;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=G protein-coupled receptor 156 {ECO:0000313|Ensembl:ENSPFOP00000007539.2};
GN Name=GPR156 {ECO:0000313|Ensembl:ENSPFOP00000007539.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000007539.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000007539.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 3 family. GABA-B
CC receptor subfamily. {ECO:0000256|ARBA:ARBA00008991}.
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DR EMBL; AYCK01020923; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A087XP36; -.
DR STRING; 48698.ENSPFOP00000007539; -.
DR Ensembl; ENSPFOT00000007551.2; ENSPFOP00000007539.2; ENSPFOG00000007604.2.
DR eggNOG; KOG1055; Eukaryota.
DR GeneTree; ENSGT00940000159755; -.
DR OMA; NCSSQCE; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0004965; F:G protein-coupled GABA receptor activity; IEA:InterPro.
DR GO; GO:0035677; P:posterior lateral line neuromast hair cell development; IEA:Ensembl.
DR CDD; cd15292; 7tmC_GPR156; 1.
DR InterPro; IPR002455; GPCR3_GABA-B.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR041946; GPR156_7TM.
DR PANTHER; PTHR10519:SF63; G-PROTEIN COUPLED RECEPTOR 156-RELATED; 1.
DR PANTHER; PTHR10519; GABA-B RECEPTOR; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR PRINTS; PR01176; GABABRECEPTR.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 55..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 293..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 53..318
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT REGION 412..518
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 361..395
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 412..439
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 457..512
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 810 AA; 90042 MW; B4D1800982A7A34B CRC64;
MEPELNCSSV CDSPLCLIQA GLSRQEGQDV LRRLCILNSL AAEVPRRSLS PALRAVVWTM
LSSGILLAFC FLVFTLRFKN NRIVKMSSPN LNVLTLLGSV LTYISGFLFA MDERAHAQAE
VSITLLQARM WMLCVGSTLV FGPILGKTWR LYRVFTQRVP DKRVIIRDIQ LIGMVVLLIL
LEILILTTWN LTDPVRCSQS VRAVAKATER DTSYSLSQLD SCSSEYSNIW LIIIAVQKGC
LLLYGTYLAG LTSNVSHPPV NQSPTIITAV TLVTFSSAVA FPVFFFLHAW PNLVYSTVAG
AIFICTLATN CMLFVPQLTQ WRQFEEDQNN PSQMAKYFSS PSKSQPSVYS QDEIYFLLGE
NSSMKKLLNE KNAAIDSLQE QVNNAKDKLL RLMTASQPLG DQDVDSSAAY LNSSSTQTTE
LPSEGSSSSC LSQGDTKSRR LPPPSPHNLT LPPDPSNVLR IPSSQNSMDL HPASSPFTDD
ILSGSRKDVP NSATRETAQS TVRGNAKQPL SPTFPGRTAE EAVHFVTSLQ NRRRLNPSRV
EQFASHGGLP MQVGPNPKLT GFVSSEKLQE IIQELSMDAV LETALRFPGQ ASKTSSQPRL
NTLSPLSLCS SHSLFQYPSV SPHAVRKRRP PFHPSRRALS SSCFYTGSDV PICELKRDTC
EHQNPDETHF RADCSVTDLD KSVEEKEGDK EEEEEAKNCQ RHASRSHNCP LWRCARQNCS
PEHGAEEDDS GKQRHRCIRD SSGYWDSDSS SSTDYCYYHR PYCDSCLQRG SFLSSDSSSD
SSDSEYEDYT NLCRPPRPVV FKDDLKPTLV
//
