ID   A0A087XP79_POEFO        Unreviewed;       741 AA.
AC   A0A087XP79;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 2.
DT   27-MAR-2024, entry version 43.
DE   RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE            EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
OS   Poecilia formosa (Amazon molly) (Limia formosa).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000007582.2, ECO:0000313|Proteomes:UP000028760};
RN   [1] {ECO:0000313|Proteomes:UP000028760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA   Schartl M., Warren W.;
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPFOP00000007582.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC         Evidence={ECO:0000256|ARBA:ARBA00001556};
CC   -!- SIMILARITY: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
CC       {ECO:0000256|ARBA:ARBA00005601}.
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DR   EMBL; AYCK01009706; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A087XP79; -.
DR   Ensembl; ENSPFOT00000007594.2; ENSPFOP00000007582.2; ENSPFOG00000007579.2.
DR   GeneTree; ENSGT00940000156024; -.
DR   Proteomes; UP000028760; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0032574; F:5'-3' RNA helicase activity; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProtKB-KW.
DR   CDD; cd18038; DEXXQc_Helz-like; 1.
DR   CDD; cd18808; SF1_C_Upf1; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR045055; DNA2/NAM7-like.
DR   InterPro; IPR041679; DNA2/NAM7-like_C.
DR   InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR   InterPro; IPR049080; MOV-10-like_beta-barrel.
DR   InterPro; IPR026122; MOV-10/SDE3_DEXXQ/H-box.
DR   InterPro; IPR049079; Mov-10_helical.
DR   InterPro; IPR049077; MOV-10_Ig-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR047187; SF1_C_Upf1.
DR   PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR   PANTHER; PTHR10887:SF537; HELICASE MOV-10; 1.
DR   Pfam; PF13086; AAA_11; 2.
DR   Pfam; PF13087; AAA_12; 1.
DR   Pfam; PF21634; MOV-10_beta-barrel; 1.
DR   Pfam; PF21635; Mov-10_helical; 1.
DR   Pfam; PF21633; MOV-10_Ig-like; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028760}.
FT   DOMAIN          308..484
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
SQ   SEQUENCE   741 AA;  84876 MW;  909788AAA4E55595 CRC64;
     PHILAPGESY RMKIHFSSDH SGLYEQLLVF KFKRDCEHSE TFDVMRLLEV IRQTPQNEDS
     QARSEAEKKF QAAKKKTLTG CEVFLRPEVY LRKYPLPQNI ADMKDMDMSV QFLISHRDLE
     KQPLKWGNYS WRFHLLLYLE EYAISTALQE CNQEDILVVT HPTEKHILIL KAEDVSNMSN
     VSLTGCMALV TPLNQQFERT YKGWVDDVDE EEIYINFEET FPEEYNMGVR CSIVFSLQRI
     PLRMQHRAAA LARKHLLRDL LFPVGLCSAY NSCLAPVIPN CTRSVCTMTE NNPEQQKAIR
     HILARSAKPA PYLIFGPPGT GKTVTLVEVI KQIVSTQDSK ILVCAPSNSA TDYLCEKILE
     ENIVPHKVFR LYSISYKVEK IPQLMHCSFN VATNSFEVPT KKQLMTYQIM VTTLQTAGRL
     VTGGIPPDYY SYIIVDEAGQ AIETECLIPI AGLLKPYSGQ VVLAGDPKQL GPIILSKIAE
     RNGLGLSMLE RLMTNVRLYR QRKTNGFNSR YMTKLLRNYR SHPAILKIPN ELFYDSELQF
     CGSLEDCLYS NWELLARKDQ DFPVMFHGVA GMKEQDLNSP SVYNMAEVDV LKEYLKSLIK
     YRRRNGVDKI GPKEIGIITP YAKQVEKIKA TFRKDKDLVK EDLENVLLKV GTVEIFQGKE
     SDVILMSTVR SNPSLTEPNQ HFSLGFVKDE KRFNVAMTRA RNLLVVVGDP RVLEIDPVWN
     KLIHYCLKER AYRGINISDL K
//