ID A0A087XRG6_POEFO Unreviewed; 209 AA.
AC A0A087XRG6;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 24-JAN-2024, entry version 41.
DE RecName: Full=Fibroblast growth factor {ECO:0000256|RuleBase:RU049442};
DE Short=FGF {ECO:0000256|RuleBase:RU049442};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000008369.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000008369.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the heparin-binding growth factors family.
CC {ECO:0000256|ARBA:ARBA00007936, ECO:0000256|RuleBase:RU049442}.
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DR EMBL; AYCK01013806; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007570796.1; XM_007570734.2.
DR AlphaFoldDB; A0A087XRG6; -.
DR STRING; 48698.ENSPFOP00000008369; -.
DR Ensembl; ENSPFOT00000008381.1; ENSPFOP00000008369.2; ENSPFOG00000008420.1.
DR GeneID; 103150953; -.
DR KEGG; pfor:103150953; -.
DR CTD; 9965; -.
DR eggNOG; KOG3885; Eukaryota.
DR GeneTree; ENSGT00940000160601; -.
DR OMA; PGCVVIR; -.
DR OrthoDB; 3092220at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0008083; F:growth factor activity; IEA:InterPro.
DR GO; GO:0007420; P:brain development; IEA:Ensembl.
DR GO; GO:0002088; P:lens development in camera-type eye; IEA:Ensembl.
DR GO; GO:0048665; P:neuron fate specification; IEA:Ensembl.
DR GO; GO:0048709; P:oligodendrocyte differentiation; IEA:Ensembl.
DR GO; GO:0008284; P:positive regulation of cell population proliferation; IEA:Ensembl.
DR GO; GO:0050769; P:positive regulation of neurogenesis; IEA:Ensembl.
DR GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR GO; GO:0031290; P:retinal ganglion cell axon guidance; IEA:Ensembl.
DR Gene3D; 2.80.10.50; -; 1.
DR InterPro; IPR002209; Fibroblast_GF_fam.
DR InterPro; IPR008996; IL1/FGF.
DR PANTHER; PTHR11486; FIBROBLAST GROWTH FACTOR; 1.
DR PANTHER; PTHR11486:SF74; FIBROBLAST GROWTH FACTOR 19; 1.
DR Pfam; PF00167; FGF; 1.
DR PRINTS; PR00263; HBGFFGF.
DR PRINTS; PR00262; IL1HBGF.
DR SMART; SM00442; FGF; 1.
DR SUPFAM; SSF50353; Cytokine; 1.
DR PROSITE; PS00247; HBGF_FGF; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Signal {ECO:0000256|RuleBase:RU049442}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|RuleBase:RU049442"
FT CHAIN 17..209
FT /note="Fibroblast growth factor"
FT /evidence="ECO:0000256|RuleBase:RU049442"
FT /id="PRO_5005106695"
SQ SEQUENCE 209 AA; 23115 MW; 6586C798B5ADFE64 CRC64;
MLLFMFILCI PGELFTLGVF CMPMMDQGPH VTHGWGQVIR LRHLYAAKPG LHLLISEDGQ
IHGSADQTLY SLLEIQPVGP GCVVIRGVAT TRFLCMESDG RLYSTQIYSR ADCTFREQIQ
ADGYNVYTSD GHGVLLSLGN NQQRHSGSDH GVPALARFLP RLNTLQQAVP TEPDVTDLLS
PDKVQETVDM VGSFGKLSHI IHSPSFHKR
//
