ID A0A087XSE6_POEFO Unreviewed; 1062 AA.
AC A0A087XSE6;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=StAR-related lipid transfer protein 13-like {ECO:0000313|Ensembl:ENSPFOP00000008699.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000008699.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000008699.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AYCK01012653; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007568720.1; XM_007568658.2.
DR AlphaFoldDB; A0A087XSE6; -.
DR STRING; 48698.ENSPFOP00000008699; -.
DR Ensembl; ENSPFOT00000008711.2; ENSPFOP00000008699.2; ENSPFOG00000008645.2.
DR GeneID; 103149467; -.
DR KEGG; pfor:103149467; -.
DR eggNOG; KOG2200; Eukaryota.
DR GeneTree; ENSGT00950000183061; -.
DR OMA; CASTLEI; -.
DR OrthoDB; 2883046at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd04375; RhoGAP_DLC1; 1.
DR Gene3D; 1.10.287.2070; -; 1.
DR Gene3D; 3.30.530.20; -; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR023393; START-like_dom_sf.
DR InterPro; IPR002913; START_lipid-bd_dom.
DR PANTHER; PTHR12659; RHO-TYPE GTPASE ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR12659:SF6; STAR-RELATED LIPID TRANSFER PROTEIN 13; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR Pfam; PF07647; SAM_2; 1.
DR Pfam; PF01852; START; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SMART; SM00454; SAM; 1.
DR SMART; SM00234; START; 1.
DR SUPFAM; SSF55961; Bet v1-like; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50238; RHOGAP; 1.
DR PROSITE; PS50848; START; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 611..817
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT DOMAIN 863..1031
FT /note="START"
FT /evidence="ECO:0000259|PROSITE:PS50848"
FT REGION 119..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 266..307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 487..524
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 124..182
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 273..295
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 497..523
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1062 AA; 120047 MW; 3FE5ACDE728B0631 CRC64;
MMKISQIEAK EACDWLRAAG FPQYAQLFED SQFPIDITPV KRDHDFLDKD LVETLCKRLN
TLNKCASMKL DVNLPKKKSE DSDEEDLFAI SDKWTFEWSS RRWSRLQDIN CLLRTHGEGQ
TSKDGLPLHS TTSRESVLTD LSEPEVSSLH SESSGGSGRR GLSTEDSDCS NRTCSDSAAM
PDLTSLTMPH IPKEFSHYRS VPDKQGKFSR TRAKDFLKRM ETLRSKGTSV RDRKTLVISS
PVMQQEAQAL KTLHCVEIVN GDAGAPELPS GRILSPQSGS EGSSHSSGST VSTPSLKERK
AHRADHKRSG MYLEDLDIFS GNQMNKVAEH NRRNEFCSYE DLVVHIPKDH KPGTFPKALS
IESLSPTNGA INWHTGSMHL DSTLISCRKE SRPVTQCCSR GSRISVYDNV PGSHLYASTG
DLIDLEKEDL FPHLDDILLH VNGLQQIVDH WSKNVLPTGE GVMQVDSEKE DTVRLQSSSQ
ITLDFEENSV TESQTTPGDG DRDKVSLAET ESTRFRERRD SGVGASLTRP NRLRWPSFQI
SNRLSHSMAS LQITNQSAGQ LSLLQKFSLL RLTAIMEKYS MSNKHGWTWS VPKFMKRTKV
PDYKDKNVFG VPLIVNVQRS GQPLPLGLQQ ALRYLRSQCL DQVGLFRKSG VKSRIHALRQ
MNESSPDNVN YEDQSAYDVA DMVKQFFRDL PEPLLTSKLG ETFLHIYQYV PKDQRLQAVQ
AAIMLMPDEN REVLQTLLCF LSDVTSSVEE NQMTPMNIAV CLAPSLFHLN IMRKDNLSPK
AMQKKYATGR PDQKDLNENL AATQGLAHMI MECNRLFEIP HEMVTQSRNS YVEADLHAPT
IDELCRQLEE DDGTYQTHLE GRLQTFLKEA REKSKYWVSC SSSDNTELYY KKVGDGNPLR
RWRVSVEVEA PPSVVLNRVL RERHLWDMDL LQWKVCETLD KQTEVFQYVL SRMPPHPSRD
FVALRSWRTD LPKGACSLVS VSIEHEDSSA TEGVRAMILE SNYLLEPCGS GKSRLTHICR
VDLKGRTPDW YNKAFGHLCA AEAARIRNSF QPLIADGPET KI
//
