ID A0A087XSI0_POEFO Unreviewed; 346 AA.
AC A0A087XSI0;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Cyclic AMP receptor-like protein A {ECO:0000313|Ensembl:ENSPFOP00000008733.1};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000008733.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000008733.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AYCK01002456; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01002457; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007547177.1; XM_007547115.2.
DR AlphaFoldDB; A0A087XSI0; -.
DR STRING; 48698.ENSPFOP00000008733; -.
DR Ensembl; ENSPFOT00000008745.1; ENSPFOP00000008733.1; ENSPFOG00000008761.1.
DR GeneID; 103134722; -.
DR KEGG; pfor:103134722; -.
DR eggNOG; ENOG502QTGV; Eukaryota.
DR GeneTree; ENSGT00510000053070; -.
DR OMA; FYSPDMT; -.
DR OrthoDB; 2952177at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0030552; F:cAMP binding; IEA:InterPro.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR022343; GCR1-cAMP_receptor.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000848; GPCR_cAMP.
DR PANTHER; PTHR23112:SF43; CYCLIC AMP RECEPTOR-LIKE PROTEIN A; 1.
DR PANTHER; PTHR23112; G PROTEIN-COUPLED RECEPTOR 157-RELATED; 1.
DR Pfam; PF05462; Dicty_CAR; 1.
DR PRINTS; PR02001; GCR1CAMPR.
DR PRINTS; PR00247; GPCRCAMP.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 33..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 63..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 27..183
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
SQ SEQUENCE 346 AA; 39847 MW; 22AA72B7F7284CC8 CRC64;
MDSRSLNNES RCVFFNSSSK DNRCAVILSV KRATGTFSLV GCVFMLFVIW LLRRYHSLAQ
KMILSLTVAA FFDSIAYVMG ETHPKGSLCN FQAWWLTYFD WSALAWVCLI TLNLYLNLVR
EISTNRYEKF YHLMAWGLPL VMASLPLLRG CYGPAGAWCW ITDDHVAWRF GIWYVPLFSL
IFLMICCYGR IICVANNRMQ SWRGTFNPER ERRKVSLAAE IKPLKWYPSV YLLVSTFPLV
NRLHNAFYPE EPSFPLTLLH VLSAPLHGLA NAFVFGLDKE WWSLLSPTGL QLALQSRLCD
RTRIGEYYPG AVRYTQADLI DPSDDDDDDT NVLFYSPDMT LKDRGP
//
