ID A0A087XTN1_POEFO Unreviewed; 917 AA.
AC A0A087XTN1;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Cytoplasmic linker associated protein 2 {ECO:0000313|Ensembl:ENSPFOP00000009134.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000009134.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000009134.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Chromosome, centromere, kinetochore
CC {ECO:0000256|ARBA:ARBA00004629}. Golgi apparatus, trans-Golgi network
CC {ECO:0000256|ARBA:ARBA00004601}.
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DR EMBL; AYCK01002738; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01002739; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01002740; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A087XTN1; -.
DR Ensembl; ENSPFOT00000009146.2; ENSPFOP00000009134.2; ENSPFOG00000008615.2.
DR GeneTree; ENSGT00940000155574; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0000776; C:kinetochore; IEA:UniProtKB-KW.
DR GO; GO:0005819; C:spindle; IEA:UniProt.
DR GO; GO:0015631; F:tubulin binding; IEA:InterPro.
DR GO; GO:0000278; P:mitotic cell cycle; IEA:UniProt.
DR GO; GO:0031110; P:regulation of microtubule polymerization or depolymerization; IEA:UniProt.
DR GO; GO:1902903; P:regulation of supramolecular fiber organization; IEA:UniProt.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 3.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR024395; CLASP_N_dom.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR034085; TOG.
DR InterPro; IPR048491; XMAP215_CLASP_TOG.
DR PANTHER; PTHR21567; CLASP; 1.
DR PANTHER; PTHR21567:SF87; CRESCERIN-LIKE PROTEIN CHE-12; 1.
DR Pfam; PF12348; CLASP_N; 1.
DR Pfam; PF21041; XMAP215_CLASP_TOG; 1.
DR SMART; SM01349; TOG; 2.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
PE 4: Predicted;
KW Centromere {ECO:0000256|ARBA:ARBA00023328};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Kinetochore {ECO:0000256|ARBA:ARBA00022838};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 8..233
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT REPEAT 169..207
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT DOMAIN 316..546
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT REGION 237..289
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 542..593
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 610..783
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 542..566
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 616..687
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 710..737
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 764..783
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 917 AA; 99966 MW; 78F0BF79056EC4A9 CRC64;
MEDHDNMDYF YQQVLQKDVT RRLQVGQDLI DYLNDPDRSP DVEQDKPRLD KTIDELTGWI
NSSNFKVALL GIDICGAFVD RLGERFKGYL GTVLPALVDR LGDGKDQVRE NSQALILRLM
EQTASPMNVW ERLTPSFKHK NFRSREGICL CLSATLGTYG AQPLSLSKLV PHLCSLTGDQ
NPQVREASIT TLVDVYRHVG EKVRADLGKR GLPAARLQMI FARFDDALNS GNMALSPSHD
RSFDDDDSVD GRSSSAQAAF KIPKVPKKAA ESSAARRPSA TSGKLVSKES AGAVDEEDFI
RAFTDVPPVQ IYSTRDLEDN LNKIREICSD DKHDWDQRCN ALKKIRSLLV AGAAGYDCFY
QHLRLLDGAF KLSAKDLRSQ VVREACITVA HLSSVLGNKF DHGAEAIVPV LFNLIPNCAK
IMATSGVSAI RIIIRHTHVP RLIPLITSNC TSKSVAVRRR CYYFLDLLLQ EWQTHSLEKH
TAVLVESIKK GIRDADSEAR VEARKTYWGL RNHFPGEADA LYNSLESSYQ RTLQSCLKSS
GSVASLPQSD RSSSSSQESL NRPLTSKWSA APGRVPAGSR GGASSVSLQR SRSDVDVNAA
AVAKYRHVGQ TKGASRLPPG SYSSLGTRSD NGRVRAKQPL STASTVSSQV DSRGRSRTKM
VSQSQPGSRS GSPGRVLTTT ALSTMSSGAH RVLGGATGDG HRRSRIPRSQ GCSRDSSPTR
LSVAPSSFSS NYNGASRGAR GSRIPRPSMS QGCSREASRE SSRDTSPVRS FTPLATRSYS
RSTGALHTPD AFGAAGSGFG ISQSSRLSSS VSAMRVLNTG SDVEEALADA LKKPARRRYE
NYNMYSDDDA NSDASSACSE RSYSSRNGGA IPTYMRQTED VAEVLNRCAS ANWSERKEGL
LGLQALLKNQ RTLRSAS
//
