ID A0A087XU81_POEFO Unreviewed; 561 AA.
AC A0A087XU81;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Sorting nexin-27-like {ECO:0000313|Ensembl:ENSPFOP00000009334.2};
GN Name=SNX27 {ECO:0000313|Ensembl:ENSPFOP00000009334.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000009334.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000009334.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AYCK01008878; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007561548.1; XM_007561486.2.
DR AlphaFoldDB; A0A087XU81; -.
DR STRING; 48698.ENSPFOP00000009334; -.
DR Ensembl; ENSPFOT00000009347.2; ENSPFOP00000009334.2; ENSPFOG00000009276.2.
DR GeneID; 103144479; -.
DR KEGG; pfor:103144479; -.
DR CTD; 566205; -.
DR eggNOG; KOG3784; Eukaryota.
DR GeneTree; ENSGT00950000183212; -.
DR OMA; HMALKKE; -.
DR OrthoDB; 2874169at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProt.
DR CDD; cd13338; FERM-like_C_SNX27; 1.
DR CDD; cd01777; FERM_F1_SNX27; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR CDD; cd06886; PX_SNX27; 1.
DR Gene3D; 1.20.80.60; -; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR037831; SNX17/27/31-like.
DR InterPro; IPR037827; SNX27_FERM-like_dom.
DR InterPro; IPR037833; SNX27_PX.
DR InterPro; IPR037835; SNX27_RA.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR12431; SORTING NEXIN 17 AND 27; 1.
DR PANTHER; PTHR12431:SF20; SORTING NEXIN FAMILY MEMBER 27; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF00788; RA; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS50200; RA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Transport {ECO:0000256|ARBA:ARBA00022927}.
FT DOMAIN 41..134
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 157..265
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT DOMAIN 269..358
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 528..561
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 561 AA; 63759 MW; C0CAD7192F928279 CRC64;
MADVGGDEIR PAHPTASRYN GPVVGSSAGQ NAATVMSGPR IVRIVKSESG YGFNVRGQVS
EGGQLRSING ELYAPLQHVS AVLPGGAADR AGIAKGDRIL EVNGVNVEGA THKQVVDLIR
AAEKELVLAV LSVPPQEADG LEGGEDVQPN YDYSDKQAVP ISIPTYKHVE QHSERFVVYN
VYMSGRQLCS KRYREFAILH QNLKREFSNF NFPKLPGKWP FSLSEQQLDA RRRGLEEYLE
RVCSVRVIGE SDIMQEFLSE SDENYNGVTD VELRIALPDK TTISVRVRKN STTDQVYQAL
VLKVGMDSIM ASYFALFEVI NHSFVRKLAP NEFPHKLYVQ NYTSAVPGTC LALRKWLFSI
QEEELLRDNP LALHYCFHQA LDDVKKGFIK TEDKSYQLQK LAEQRKMATY LSLLRTCEGY
NEVAFPHCSC DSRRKGHVIT AISVHHFKLH ACTEDGTLEN QVIAFEWAEM QRWDTDEEGM
AFCFEYARGE KKPRWVKIFT PYFNYMHECF ERVFCELKWR KQVEEEESDK DNKNCSNNEY
LPPLETQQKG WRHLGGEIAT S
//
