ID A0A087XZE0_POEFO Unreviewed; 867 AA.
AC A0A087XZE0;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=G-protein coupled receptors family 3 profile domain-containing protein {ECO:0000259|PROSITE:PS50259};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000011143.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000011143.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AYCK01005726; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A087XZE0; -.
DR STRING; 48698.ENSPFOP00000011143; -.
DR Ensembl; ENSPFOT00000011159.1; ENSPFOP00000011143.1; ENSPFOG00000011111.1.
DR eggNOG; KOG1056; Eukaryota.
DR GeneTree; ENSGT00940000162782; -.
DR OMA; LYKLPMV; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd15283; 7tmC_V2R_pheromone; 1.
DR CDD; cd06364; PBP1_CaSR; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR004073; GPCR_3_vmron_rcpt_2.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24061:SF418; C-FAMILY ODORANT RECEPTOR OLFCQ19-RELATED; 1.
DR PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR01535; VOMERONASL2R.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 598..623
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 635..657
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 669..693
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 714..734
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 754..782
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 794..814
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 826..849
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 599..864
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 867 AA; 96333 MW; 96B97FBD0530DD0A CRC64;
MNIYQFMIYS SLFFSESSFL SSSCKLLRTF YLNGLHKPGD VTLGGLFEVH YSSVFPEQTF
TSAPHQPSCQ GFDTLGFRHA MTMAFAVDEI NKNPSLLPNV TLGYSLYDNC ATLSIGFSAA
LAMASGQEER FSIQESCSGT PPVVGIVGDP FSTFSIAASD VLGLYRLPMV SYFATCSCLS
DRQRFPSFFR TIPSDAFQVR AMIQILKHFG WTWAGLLVSD DDYGLHVSRS FQTDLTRSGG
GCLAYTEVLP WGDNPREYQR IVDVMTKSTA RVVIVFAHQM HMIQLLEQVV KQNVTGLQWI
ASEAWTLLEG LQISAFMPFL GGTLGIAVRR GEIPGLRDFL LRIRPDQNNI SENNMVKLFW
EHTFQCKFLP PPAGSVEDAG AQCSGREDLN SVTTDLLNVS ELRPEYNIYK AVYALAHALN
DMLSCVPGRG PFSGNTCASL QTLELWQLMH YLERVNFTTP FGDQVTFDEN GDALPIYDIM
NWIWLPDGRI KVQSVGEVQR SASKEEELTI DEVKIFWNFE SKKPPRSVCS DSCPPGTHMV
RRKGEPLCCF YCIPCSEGKV SNQTDSLECF SCPEDFWSSP QRDHCIPKKT EFLSYQEPLG
ICLTVTSLLG TSICAIVLGI FTYHRGTPIV RANNSELSFL LLVSLKLCFL CSLLFIGRPI
LWTCQLRHAA FGISFVLCVS CILVRTMVVL AVFKASKPGG GAYLKWFGAV QQRGTVFALT
CVQVAICTAW IVTASPAPHK NTQYHNDKIV YECVVGSIIG FSALLGYISV LAILSFVLAF
LARNLPDNFN EAKLITFSML IFCAVWVAFV PAYINSPGKY ADAVEVFAIL ASSFGLLVAL
FGPKCYIILL RPERNTKKAI IGYRTTK
//
