ID A0A087Y2C3_POEFO Unreviewed; 368 AA.
AC A0A087Y2C3;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Nuclear factor of activated T cells 4 {ECO:0000313|Ensembl:ENSPFOP00000012176.2};
GN Name=NFATC4 {ECO:0000313|Ensembl:ENSPFOP00000012176.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000012176.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000012176.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AYCK01004650; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01004651; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A087Y2C3; -.
DR STRING; 48698.ENSPFOP00000012176; -.
DR Ensembl; ENSPFOT00000012193.2; ENSPFOP00000012176.2; ENSPFOG00000012167.2.
DR eggNOG; ENOG502RIHQ; Eukaryota.
DR GeneTree; ENSGT00940000160923; -.
DR OMA; SHACNEE; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0043227; C:membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.40.340; Rel homology domain (RHD), DNA-binding domain; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR008366; NFAT.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR032397; RHD_dimer.
DR InterPro; IPR011539; RHD_DNA_bind_dom.
DR InterPro; IPR037059; RHD_DNA_bind_dom_sf.
DR PANTHER; PTHR12533; NFAT; 1.
DR PANTHER; PTHR12533:SF11; NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 4; 1.
DR Pfam; PF16179; RHD_dimer; 1.
DR Pfam; PF00554; RHD_DNA_bind; 1.
DR PRINTS; PR01789; NUCFACTORATC.
DR SMART; SM00429; IPT; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS50254; REL_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000028760}.
FT DOMAIN 27..214
FT /note="RHD"
FT /evidence="ECO:0000259|PROSITE:PS50254"
FT REGION 347..368
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 368 AA; 40524 MW; 9FA4F189A47D71A9 CRC64;
MDYLPVPPAL AWGRTRASAH SPLFRSNALP PLDWPLPSQF DQFELRIEVQ PRPHHRAHYE
TEGSRGAVKA APTGHPVVKL CGYVERKPLS LQVFVGTADD RSIRPHPFYQ IHRVTGKMVG
TASHESVQAG TKLLDIPLNP ENNMTALIDC AGILKLRNSD IELRKGETDV GRKNTRVRLV
FRTHLPVAPP VGPPGRVLAL QVASLPIECS QRSAQELPVI ESVSVTSCSV EGGEELLLSG
TNFLPISRVL FMERGTGTSD GKLQWEEEAH VDRDNSNECL LCVRVPAYSD LSVSRPVSVS
LYVSNGKRKR SSTHCFKYLP VNFKESPLAN SPLPPIPTSP FPQYSAYPQE LCPSPPSNPY
QDACSAPY
//
