ID   A0A087Y3N3_POEFO        Unreviewed;       890 AA.
AC   A0A087Y3N3;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 2.
DT   27-MAR-2024, entry version 49.
DE   SubName: Full=Transportin 2 {ECO:0000313|Ensembl:ENSPFOP00000012636.2};
OS   Poecilia formosa (Amazon molly) (Limia formosa).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000012636.2, ECO:0000313|Proteomes:UP000028760};
RN   [1] {ECO:0000313|Proteomes:UP000028760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA   Schartl M., Warren W.;
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPFOP00000012636.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; AYCK01009552; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_007562988.1; XM_007562926.2.
DR   AlphaFoldDB; A0A087Y3N3; -.
DR   STRING; 48698.ENSPFOP00000012636; -.
DR   Ensembl; ENSPFOT00000012653.2; ENSPFOP00000012636.2; ENSPFOG00000012466.2.
DR   GeneID; 103145474; -.
DR   KEGG; pfor:103145474; -.
DR   CTD; 30000; -.
DR   eggNOG; KOG2023; Eukaryota.
DR   GeneTree; ENSGT00940000156708; -.
DR   OMA; ACDFWVQ; -.
DR   OrthoDB; 276400at2759; -.
DR   Proteomes; UP000028760; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000357; HEAT.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR040122; Importin_beta.
DR   PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR   PANTHER; PTHR10527:SF17; TRANSPORTIN-2; 1.
DR   Pfam; PF02985; HEAT; 1.
DR   Pfam; PF13513; HEAT_EZ; 1.
DR   Pfam; PF03810; IBN_N; 1.
DR   SMART; SM00913; IBN_N; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   4: Predicted;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          31..99
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50166"
FT   REGION          325..366
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        329..349
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        350..366
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   890 AA;  100453 MW;  1030ABF1A010A327 CRC64;
     MEWQPDEQGL QQVLQLLKDS QSPNTVTQRA VQQKLEQLNQ FPDFNNYLIF VLTRLKTEDE
     PTRSLSGLIL KNNVKAHYQN FPSGVSDFIK RECLNSIGDP SPLIRATIGI LITTIASKGE
     LQSWPELLPQ LCNLLDSEDY NTCEGSFGAL QKICEDSSEL LDSDALNRPL NVMIPKFLQF
     FKHCSPKIRS HAIACVNQFI IGRAQALMDN IDTFIESLFV LAADEDSEVR KNVCRALVML
     LEVRIDRLIP HMHSIIQYML QRTQDPDENV ALEACEFWLT LAEQPICKEA LSGHLVQLIP
     VLVNGMKYSE IDIILLKGDV EEDEAVPDSE QDIKPRFHKS RTVTLQHEGG EGEEDEDIDD
     EDDDDDDDAL TDWNLRKCSA AALDVLANVF RDELLPHLLP LLKGLLFHPD WVIKESGILV
     LGAIAEGCMQ GMVPYLPELI PHLIQSLSDK KALVRSIACW TLSRYAHWVV SQPPDSYLKP
     LMTELLKRIL DSNKRVQEAA CSSFATLEEE ACTELVPYLS FILDTLVFAF GKYQHKNLLI
     LYDAIGTLAD SVGHHLNQPE YIQKLMPPLI AKWNQLKDED KDLFPLLECL SSVATALQSG
     FLPYCEPVYQ RCVTLVQKTL AQAMMYNQHP DQYEAPDKDF MIVALDLLSG LAEGLGGHVE
     QLVARSNIMT LLFQCMQDTM PEVRQSSFAL LGDLTKACFL HVKPCIAEFM PILGLNLNPE
     FISVCNNATW AIGEISMQMG AEMQPYVGMV LPHLVEIINR PNTPKTLLEN TAITIGRLGF
     VCPQEVAPQL QHFIRPWCTS LRNIRDNEEK DSAFRGICVM IGVNPAGVVQ DFIFFCDAVA
     SWVNPKDDLR DMFYKILHGF KDQVGEENWQ QFSEQFPPLL KERLSACYGV
//