ID A0A087Y659_POEFO Unreviewed; 1397 AA.
AC A0A087Y659;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Condensin complex subunit 1 {ECO:0000256|PIRNR:PIRNR017127};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000013512.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000013512.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Regulatory subunit of the condensin complex, a complex
CC required for conversion of interphase chromatin into mitotic-like
CC condense chromosomes. The condensin complex probably introduces
CC positive supercoils into relaxed DNA in the presence of type I
CC topoisomerases and converts nicked DNA into positive knotted forms in
CC the presence of type II topoisomerases.
CC {ECO:0000256|PIRNR:PIRNR017127}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CND1 (condensin subunit 1) family.
CC {ECO:0000256|ARBA:ARBA00009606, ECO:0000256|PIRNR:PIRNR017127}.
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DR EMBL; AYCK01003757; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007550177.1; XM_007550115.2.
DR STRING; 48698.ENSPFOP00000013512; -.
DR Ensembl; ENSPFOT00000013531.2; ENSPFOP00000013512.2; ENSPFOG00000013227.2.
DR GeneID; 103136732; -.
DR CTD; 9918; -.
DR eggNOG; KOG0414; Eukaryota.
DR GeneTree; ENSGT00940000153566; -.
DR OMA; CPLEKLW; -.
DR OrthoDB; 5480287at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007076; P:mitotic chromosome condensation; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR026971; CND1/NCAPD3.
DR InterPro; IPR032682; Cnd1_C.
DR InterPro; IPR007673; Condensin_cplx_su1.
DR InterPro; IPR024324; Condensin_cplx_su1_N.
DR PANTHER; PTHR14222; CONDENSIN; 1.
DR PANTHER; PTHR14222:SF2; CONDENSIN COMPLEX SUBUNIT 1; 1.
DR Pfam; PF12717; Cnd1; 1.
DR Pfam; PF12922; Cnd1_N; 1.
DR PIRSF; PIRSF017127; Condensin_D2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|PIRNR:PIRNR017127};
KW Cell division {ECO:0000256|ARBA:ARBA00022618,
KW ECO:0000256|PIRNR:PIRNR017127}; Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW DNA condensation {ECO:0000256|ARBA:ARBA00023067,
KW ECO:0000256|PIRNR:PIRNR017127};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776, ECO:0000256|PIRNR:PIRNR017127};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760}.
FT DOMAIN 74..236
FT /note="Condensin complex subunit 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12922"
FT DOMAIN 1067..1227
FT /note="Condensin complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12717"
FT REGION 491..516
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 575..599
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 942..969
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1292..1397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 495..512
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 942..964
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1397 AA; 155596 MW; A8F5D7898E01BB01 CRC64;
MSWDFFVPVC VGDLVKTGGI NQYVVQDVVP AKQLPSHLNK FKMGLRSQGP SCILEHFDTG
YSVLQHFNSL ELGVKEDTLE LLVKVVSDLA VSLPTALTST TFSAAERKEK LNAVKMSVFL
LCKLTESLES VSYRQSIVTA PGKGSKKGKG GGEGLLQWDS ERERVLHALV QLLQLDIRSL
WSLSLVEEEF ISCVTCCCYK LLENPTISHV KNKPTRDCII HLLGLLITKY NHLLGASVKV
IQMLQHFEQL SSVFAQAVSV WSTEYGVRAI IGEVIREIGQ KSSEELAREG SGVKAFASFL
SELSGLVPEL MIPNISVLIT HLEGESHTMR VAVCEVLGEI LVRVLCGDGL DESGRADRDR
FFDILQEHLH DTHSHVRARV LQVFTRIVNS KALPLCRYSE VMGFAVGRLV DKSINAVKSA
IQLLAAFIAH NPYSCKLSSA DLKKPLETET AKLREMKEKL EGKAPVAVIK ASELWAAMEP
ELLVTVRTTL EPTSEAEEEN EEGGEAEDEK PEDDDRATAV KIAQYLRVNK YRNAVKLCVK
AHSWFPESEM FASLSTVTPE SLMDTLGLIF KGSDEDASDA SQNLPPTPQK EGEKEGDEGD
LKKQEMLVQY LRNMETFSLQ VEQAISVINN MLYLKTTSVV QEAVQFCVTV HEFSVANSVS
GVRKMLPLVW STDAAIKDAV VQAYRRLYLN PQGDTVRVKA QTLVDSLSEL MVDASLGTIQ
CLEEIVQEFF GSGSNLQSTV IQVLWERFTG KREASVLHKR AAVLLLGMAA RAEREVVLSN
LDTLCSVALG EKVTEDFLLA RDTVITICSI TDHVRQSKGA PFRLPQDHQL FTCLTQAVAD
GVVMEDPYWQ SFMEQAVRLI YFLAESPDQL CSRLLQRSAR LLLDQIAEGG EVNKDVGQIH
DASQDSSDQE EQVNCVCLAQ LLALCGCVAF WQVSHLERSV SAELRRRRGE TEEREEKEKG
PGSKAKQLAN ESAMEEELGL IGATAEDTEA ELIRKICETE LLAEDNLLSA FLPLLVKVCS
SPGRYSHPQL TTAACLALSQ YMMISPSVCE DNIRLIFTVL ERSTLPVVRA NSIIALGDLT
VRFPNILEPW TQNLYARLSD EVPSVRQTAV TVLTQLVLKD VLKVKGQVSE VAVLLIDPEP
HITSLALNFF NELATKDNAI YNLLPDIISR LSDPERGMSS EDFNTIMKQL FSYITKERQT
ESLVEKLCQR FRTAKTERQW CDLAMSLSLL SMCERGFKRL QECWECYSDK LTESGVYQPL
LTITAKLRRG AKPQFKAQID DFEKRLTAVH TRGLENVESP EMEENQGEEG TSETTSSRTL
LPTRGRQKRR GQTKSSVSSH GDDSFVTPQK SRKAKKPVIS FSSDEEEDED DAVMAESETP
KVTTPISRTS RRTRLRN
//
