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Database: UniProt
Entry: A0A087Y7Z3_POEFO
LinkDB: A0A087Y7Z3_POEFO
Original site: A0A087Y7Z3_POEFO 
ID   A0A087Y7Z3_POEFO        Unreviewed;      2824 AA.
AC   A0A087Y7Z3;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 2.
DT   07-OCT-2020, entry version 31.
DE   SubName: Full=Centromere protein F {ECO:0000313|Ensembl:ENSPFOP00000014146};
OS   Poecilia formosa (Amazon molly) (Limia formosa).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000014146, ECO:0000313|Proteomes:UP000028760};
RN   [1] {ECO:0000313|Ensembl:ENSPFOP00000014146, ECO:0000313|Proteomes:UP000028760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=female {ECO:0000313|Ensembl:ENSPFOP00000014146,
RC   ECO:0000313|Proteomes:UP000028760};
RA   Schartl M., Warren W.;
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPFOP00000014146}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2014) to UniProtKB.
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DR   EMBL; AYCK01003644; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AYCK01003645; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AYCK01003646; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AYCK01003647; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 48698.ENSPFOP00000014146; -.
DR   Ensembl; ENSPFOT00000014166; ENSPFOP00000014146; ENSPFOG00000014027.
DR   eggNOG; ENOG502QVMD; Eukaryota.
DR   GeneTree; ENSGT00730000111187; -.
DR   OMA; YNAQLVQ; -.
DR   Proteomes; UP000028760; Unassembled WGS sequence.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR   GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR   GO; GO:0060271; P:cilium assembly; IEA:Ensembl.
DR   GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 4.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 2.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028760}.
FT   DOMAIN          1..306
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          1851..1991
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2089..2233
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2757..2801
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          124..146
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          229..290
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          453..476
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          558..587
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1451..1484
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2216..2241
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2277..2302
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2663..2786
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          20..82
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          162..196
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          620..651
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          659..686
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          694..767
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          826..846
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          882..969
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          974..994
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1047..1067
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1079..1099
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1121..1155
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1186..1234
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1500..1534
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1585..1619
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1628..1662
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1740..1781
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1855..1889
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1894..1914
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1974..2022
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2037..2057
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2065..2211
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2475..2495
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2557..2644
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        127..146
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        251..289
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        558..581
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1463..1484
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2277..2300
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2680..2703
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2704..2722
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2725..2741
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2755..2770
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2824 AA;  322609 MW;  ED18C84CFE2BEEB0 CRC64;
     MSWAVEEWKD GLPGKALQKI QEMEAQLDKL KKERTQKQFQ LDSLEAALQK QKQKVDSERT
     EISALKRENQ SMIESCDALE KTRQKVVHDL GVKEQQVSYL EGQLNSCKKT IDRLEQELKK
     YKTELDRTQP AGSSSLSTSS SDLQTFSTPQ KTFATPAPVA AHRQQDGKLE ELQEKYNHEV
     EERRKLESEL KMLQVKLLNQ SSVSHKDIAA RQAGSSIFPW QQQDQVHSLR GQDVMETPLK
     RRGASLWATQ EETPIKPSQR MSSSRTVQSP GGSSQQTEQL KSLNQGSELR GRVSELERNL
     AAQEKEIRNQ ASKLQELQTH LNQTRKELAE RDRELAKAGH ELSQAADRHQ QLQAKCSLVE
     QKLKQVSEEM SCQRHNAESC RRALEQKLKD QERNSQKELA QLQSSHQVLD QQLNQTRTKL
     TQEVQQAKKD HNVLQADMEK LRLQKNQMER EIEEQKQKLL RSEQGLQATQ TKEQDLRKKM
     EELQKEKSGA TIQLDRSSRL LTQLEEEKRI SEQSLKRTQG QLEDLKAKSE GQAEELKRLQ
     SKLEQQTQAA ARELEQMKKT LSDAEAQSDK SQTELQKQKQ ESEKLSNTLT VVEKESEALK
     SNLRQSQDEC QAVKLEHQAL LEWKKNKENL INQTEAVQQE LTDKIITLED KASLMHEANN
     KLQDQISSME ADKASLSAHI DALKGELLMR STELEEKQHQ YQQLQLHVSE AEQKHGKELE
     NAGKQLAQLQ GQVKELESRL QRETSRAELA EKTISELQEE HQAACDLLHS KDQLLELGLA
     EVSQLKDSLA QSAAQQEAQS DRLDTDSLET FVMQKAVLLK QCEESVSAQA EETERVKLQA
     EEVQQELLLS RHKICKVTKY YSCSPHSVLK YITSMEQILK VQEQLGAELQ KQIKTMSDKE
     EELTKTCEEK SEELKRLEEE LKVQRSRTEE TEQQLRAAEA QILSVENQKA ELENRLQEMK
     TEAEILQFSH TERINALQEQ ILCLEKQVAA NQEAAEEVPV LKNKLDVVNQ SLAHLNKSLE
     ASEKCLSSAN EIKAGLEATW SEKVKLITAL EDQINNLTEK LRKESESHSS EVGDLANKER
     SLKEQLEAIK QSAAAAKAES SSRREEIRTM KATLSAASRG LEERDNTIKS LKEKLDKAEA
     EQAKASELLK EKTVAMNKIK IKVQLEMLQM DLEDNESAMT SVDSQVEELK GTIASLEAML
     EDSKAQVSVL ETRLDEVQSQ NSLLETKYVT AKEELLERSC EITRLEEDAV RRQQLEESVS
     ALEAKLSQIT EENSKAETEL RQIIQEKGSR LDQLNEEKND LQASLTLLMD EQKQAETEIT
     RVKAGKEELE ERMSDLLKEI QQLHADVGEL SEQKQEAEAT IDQMAAETQQ TESALRRVSE
     EKAQLDVALS SVSEEKVELQ ERLSALTSEN RELVCKVQQV EEEKLQLESK FSEISEENAK
     LQSEMNRLTA EKQQLQTSAE RLQEQLDTRD ETSHTESRER PLLNRNQQFE VEQAALHQKL
     SVLQMELAVL QQQCDLLLQQ VDQQQRIIQQ LNNIKITLKD TNKQIILKFL QQVVVLEEAL
     EGEVRRLSQS LESSLLEKGE IASRLNSTQE EVRQMRTGIE KLQVRIESDE RKKKNMGELL
     KETRLCVSAA AQRKSDSLQD RIDALEREKD EFEQNLEEAM LQCSLDLVNI LFVTSSHDKN
     GLVKDLKNNV KLSDVILNEL EVLLTSMCPS GDESWPVKDV DAEMKQQGEP KTLWSEFDLL
     TSELQLRAEL EVQAQKLEEK VQAAEEQLSS ALEEKKSLSD QVGGRNDVTQ LLEERDSLSL
     QLETSRCQLT DAMEMLEGLE MAKEFLCNSS KISLYTLNKT ILTSLSCSSG WDEKFLQQES
     ELKRVRSEKA NLEQHILGME SELESMQAES CRLTEELETQ RKTYSGRIQQ IEALLSETTQ
     LRAELVSCSE DRDELSQSLG HWRDKVHGLE KTNLETRNLI SILEEDIRVG RKEYESLQSG
     MERVKAEREQ FLQQVVVLEE AISKHNREKE GLLSHLHEME EDHTSTNQNT ESMAGKIQAL
     EGEVRRLSQS LESSLLEKGE IASRLNSTQE EVRQMRTGIE KLQVRIESDE RKKKNMGELL
     KAAQRKSDSL QDRIDALERE KDEFEQNLEE AVLQAEAAKA ELEEERSKVE EEKKELNEKL
     TELSAALDTL RSEKAHLERE LDMKNVEIEE LKAATDKLEQ GLEKAEVEEL EKWTREEAER
     QSVRVGDLQG QLTESERENN DLRTTIESLG EEIKDLKTLA QAKEEEILTL EKEKENKAES
     FAAEKKQLEE RNEQLEQERD ELQSALVSVS QEKAKADQEK TELEEKRVKL QSKISLVETE
     KQNLQQTVSS LEQEKLRLEA ETEELQSSLL MMEEEKNNLS SALSLLEEEK QQATEEKERL
     TQEHEALQKT VASMEEELET RKRSMTQISE QHQAETCPVW CRGTKNVLSF YIFKVLNWSK
     MNVLHMQYSL LCIQVSELTS SLARLTKERD SALSKINLWM KACKQLEQEK QNILSSSGVI
     HQQLVLSYFK HTKIFALETG QKLLGKILYF SKGGRSSEEL QAEATQLRSE AEVRRKEVEE
     LKTALEKKTA EAEQKEGEVK ERAAALEGVR AEKERELEEI RKELDEVNAL LEEKSTEADE
     SMEKYCSLMV KVHKLEESND ALKTRLEQLA ASQPANEAKA PPETHRRSAR KSSSRHQEEK
     MSENTENVVP TTTASSPQGS SPGKRGHKEI SDRDGAQEAL HNLTKKLKAN TATPRGRGEQ
     DDEEFRPEGL PDLVQKGFAD IPLGEASPYI IRRTTGRRCS PWLAARQTQP AVKSDPFVAC
     RSDS
//
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