ID A0A087Y8Z7_POEFO Unreviewed; 521 AA.
AC A0A087Y8Z7;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Testin {ECO:0000256|ARBA:ARBA00019588};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000014500.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000014500.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell junction, focal adhesion
CC {ECO:0000256|ARBA:ARBA00004246}.
CC -!- SIMILARITY: Belongs to the prickle / espinas / testin family.
CC {ECO:0000256|ARBA:ARBA00008268}.
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DR EMBL; AYCK01013452; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A087Y8Z7; -.
DR STRING; 48698.ENSPFOP00000014500; -.
DR Ensembl; ENSPFOT00000014522.1; ENSPFOP00000014500.1; ENSPFOG00000014458.1.
DR eggNOG; KOG1704; Eukaryota.
DR GeneTree; ENSGT00940000155993; -.
DR OMA; NFSCHQC; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd09413; LIM1_Testin; 1.
DR CDD; cd09416; LIM2_Testin; 1.
DR CDD; cd09419; LIM3_Testin; 1.
DR CDD; cd09829; PET_testin; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 3.
DR InterPro; IPR034958; LIM1_Testin.
DR InterPro; IPR034959; LIM2_Testin.
DR InterPro; IPR034960; LIM3_Testin.
DR InterPro; IPR010442; PET_domain.
DR InterPro; IPR033724; PET_testin.
DR InterPro; IPR047120; Pk/Esn/Tes.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR24211; LIM DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24211:SF1; TESTIN; 1.
DR Pfam; PF00412; LIM; 2.
DR Pfam; PF06297; PET; 1.
DR SMART; SM00132; LIM; 3.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 2.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 2.
DR PROSITE; PS51303; PET; 1.
PE 3: Inferred from homology;
KW Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 168..275
FT /note="PET"
FT /evidence="ECO:0000259|PROSITE:PS51303"
FT DOMAIN 333..396
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 398..458
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT REGION 281..313
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 521 AA; 56697 MW; 9BFB81B6F0388DEC CRC64;
MEIEKEMKKV TLGHEFGAGA ACLKCKDKCE GFELHFWRKI CRNCKCGLAE HDVSMNSEEN
KKVGKLFEDT KYTGLIAKLK TDGIPSYQGN MVTITLPSPN TAYTVPPMAS STMVPPSPTA
AYAQPAVTSP GPVPIGSPAQ AQGKPLVLST HVTVTPVKAN KVPVTANVTA ANAVPVPKDV
PMRSVTYEWA PPVANKHLAV RYIELLPPEK RPVAGTQGAA YRRHQMDRQL PEHDQDPSKC
HELSPAEVKQ MQQYVRKCKD EALGVGDVLL PEEMAQIQAG GAGAAAAGSG GTPGRATPGS
GTDQSAGLRP ARGSLGTAAT AGAINSGLPQ NNFSCHHCKK PMLLGEPAVY AERAGYDKLW
HPACFVCCTC SELLVDMIYF WKKGKMYCGR HYGDSEKPRC GGCDELIFSN EYTQAEGQNW
HLKHFCCFDC DCILAGETYV MENDKPICKP CYMKNYAVKC ASCQKAVEPE AQRVSYGEHH
WHAEPDCFKC SGCTKCLIGQ RFMAVKNCLF CSVECKKKVM T
//
