ID A0A087Y9I9_POEFO Unreviewed; 1361 AA.
AC A0A087Y9I9;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Adenosine deaminase RNA specific {ECO:0000313|Ensembl:ENSPFOP00000014692.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000014692.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000014692.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AYCK01006460; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007556145.1; XM_007556083.2.
DR RefSeq; XP_016528902.1; XM_016673416.1.
DR SMR; A0A087Y9I9; -.
DR STRING; 48698.ENSPFOP00000014692; -.
DR Ensembl; ENSPFOT00000014714.2; ENSPFOP00000014692.2; ENSPFOG00000014636.2.
DR GeneID; 103140790; -.
DR KEGG; pfor:103140790; -.
DR CTD; 103; -.
DR eggNOG; KOG2777; Eukaryota.
DR GeneTree; ENSGT00940000157243; -.
DR OMA; ERMQMKR; -.
DR OrthoDB; 118472at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0003726; F:double-stranded RNA adenosine deaminase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd19915; DSRM_DRADA_rpt3; 1.
DR Gene3D; 3.30.160.20; -; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR002466; A_deamin.
DR InterPro; IPR044457; ADAR1_DSRM_3.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR InterPro; IPR042371; Z_dom.
DR PANTHER; PTHR10910:SF107; DOUBLE-STRANDED RNA-SPECIFIC ADENOSINE DEAMINASE; 1.
DR PANTHER; PTHR10910; EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN; 1.
DR Pfam; PF02137; A_deamin; 1.
DR Pfam; PF00035; dsrm; 3.
DR Pfam; PF02295; z-alpha; 2.
DR SMART; SM00552; ADEAMc; 1.
DR SMART; SM00358; DSRM; 3.
DR SMART; SM00550; Zalpha; 2.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 3.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS50141; A_DEAMIN_EDITASE; 1.
DR PROSITE; PS50137; DS_RBD; 3.
DR PROSITE; PS50139; Z_BINDING; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00266}.
FT DOMAIN 246..312
FT /note="Z-binding"
FT /evidence="ECO:0000259|PROSITE:PS50139"
FT DOMAIN 402..467
FT /note="Z-binding"
FT /evidence="ECO:0000259|PROSITE:PS50139"
FT DOMAIN 604..672
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 735..803
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 860..928
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 996..1328
FT /note="A to I editase"
FT /evidence="ECO:0000259|PROSITE:PS50141"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 46..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 109..197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 328..396
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 712..733
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..69
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 133..166
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 176..197
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..360
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 361..396
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1361 AA; 149148 MW; 9ACEA5A75B42931E CRC64;
MSRGRGGPYK EHFYRRPPPH LQAKENYYRP VQAQFFHGEN PDLIQNLNYY NHPGGAPQPP
RPLHPSAPPE PSHIRLAAAS DYIHNQGQGG SPAPNSFLCK QAEFLRGQST EAPQFRSSHR
GGGAPFSRPP SSPYQAPSGY IRHSNPGSSP RGRGGFSPNQ IFRYSSGPRA TGGALGPRLQ
NQNQFQGRTS YNQSSNRQCW PQTESLCDRF HNLSLQQDQS SRGRERFDRY PFPSSSTESR
FERVNITFTP DIQEQVHRAL AALKSGERIS AKVLARRIHL PKKTVNKALY SLERLHRAYK
QEVLPPLWSL YRAEGDYVSD SKTPASYLYF GPEHPQTAET EADPEKEIKG QVKEEDSDTE
SNSSYSSSSE SFDSEKAQSA AESQNEKDRP NTTSCTHQEA TCPIMANSKE QVLQFLLDVG
EATALVIAKN LGLKNAKQIN PTLYALEKQG EVNRDSDVTP PKWMLSAHRK ERMERSLKIA
KSASVFGSHM GMEIFKEEDT ASADFLSTLP PVPGLEPLPL LEDLLPEQSQ SIELPVLLSE
DKGPGEQLWA SDEIPEYLNA IRRQTDAKKM AEQQDGAVGT VAVSVAAPPP QNLRAKLQEV
RLKNPVSGLM EYAQYLGQNC EFQLLDQSGP SHDPRFRMQV MLNGKLFPIA EASSKKVAKK
DAAAAALRIL IGEIQGGPGP LEEANAAGVD QMLDILPDTS GSVENMSGTF GSNNVEVPGE
GPRQPLSRSL PGGKNPVSVL MEYSQRSGNS IEFINTGQAG PPHDPRFMFR VKVGDTTFAE
ASAPSKKAAR QLAAEEAVKE LMADGKLQVS KPQLPLGPSF EGDGGAFRAT CPSLPPLTAS
ELQAAHEAGV GDLINHLNNN AVSGLLEYAR ARGFAAEIRL VSQSGPPHDP KFTYQAKLGG
RWFPPVCASN KKQGKQEAAD AALRVLIGEA ERAARTGELI PTELPVSGST LHDQIAMLSH
QRFNALTTRI QHSLLGRKIL ATIVMRRGEG LGTVVSLGTG NRCVKGEELS LKGETVNDCH
AEIISRRGFI RFLYSELLKH YDGADDSIFE PAEENKLKIK PDITFHLYIS TAPCGDGALF
DKSCSEAGDE IEGHKPLFEN AKQGKLRTKV ENGEGTIPVE SSAIVPTWDG IQHGERLRTM
SCSDKILRWN VLGLQGALLS HFLHPIYLKS ITLGYLYSHG HLTRAVCCRL ARDGEAFSHS
LPPPFTLNHP EVGRVSVYDS TRHTGKTKES SVNWSFPDQH NVEVLDGTKG KLDGNKQAMS
RVSKSNLFCL FRSLCQRCNR TDLLSLPSYA QAKTSAVPFQ LAKQLFFEAL CIHGYGAWIG
KPLEEKSFEV SEGTRNNGGS VPLGVGNSKN GGLVEYKQAE A
//
